oxoglutarate dehydrogenase (lipoamide)

 jump to detail

Synonym

alpha-ketoglutarate dehydrogenase, Ogdh, 2210412K19Rik, oxoglutarate dehydrogenase (lipoamide), mKIAA4192, AA409584, Alpha-ketoglutarate dehydrogenase, KIAA4192, 2210403E04Rik, d1401

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:305.60 cerebellum:110.50 brain stem:31.80 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:229.30 spine:94.60 retina:192.90 eye:190 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:287.50 spleen:171.20 thymus:108.70 bone marrow:205.10 adipose:- bone:250.50 skin:506.70
GeneChip cerebrum:9.75 cerebellum:10.04 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.04 spine:10.35 retina:8.70 eye:8.44 artery/aorta:- vein:8.70 lymphnode:9.56 peripheral blood:- spleen:9.67 thymus:- bone marrow:9.68 adipose:10.84 bone:9.34 skin:9.63
CAGE cerebrum:4.78 cerebellum:- brain stem:5.04 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.98 retina:- eye:- artery/aorta:6.56 vein:- lymphnode:4.35 peripheral blood:- spleen:4.23 thymus:4.39 bone marrow:- adipose:- bone:4.94 skin:4.33
RNA-seq cerebrum:44.45 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:220.90 prostate:185.30 ovary:114.90 testis:147.80 heart:1320.70 muscle:461.60 esophagus:- stomach:229.10 intestine:147.90 colon:211.50     liver/hepato:144.80        lung:140.60    bladder:198.50 kidney:814 pituitary:129.20 thyroid/parathyroid:562.40 adrenal gland:- pancreas:84.40 breast:199.20 salivary:540
GeneChip uterus:9.63 placenta:9.13 prostate:9.65 ovary:9.98 testis:8.69 heart:12.39 muscle:11.54 esophagus:- stomach:10.96 intestine:11.09 colon:- liver/hepato:9.96 lung:10.11 bladder:9.65 kidney:11.22 pituitary:10.44 thyroid/parathyroid:- adrenal gland:10.62 pancreas:8.68 breast:10.30 salivary:9.98
CAGE uterus:4.31 placenta:4.37 prostate:4.48 ovary:4.42 testis:5.34 heart:- muscle:- esophagus:- stomach:5.22 intestine:5.67 colon:5.92     liver/hepato:5.02    lung:4.73 bladder:4.41 kidney:- pituitary:4.88 thyroid/parathyroid:- adrenal gland:4.88 pancreas:3.89 breast:4.47 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:67.68 esophagus:- stomach:- intestine:- colon:-     liver/hepato:19.01        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_010956
Gene ID 18293
Unigene ID Mm.276348
Probe set ID 1451274_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020456

Orthologous Gene

Human[3]  NM_001003941, NM_001165036, NM_002541
Rat[1]  NM_001017461, NM_001165036, NM_002541

Chromosomal Region

11A1  [6,191,636  -  6,256,645]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1606619
8248240
8889548
10349636
10725249
11042159
11076861
11217851
12466851
12477932
12520002
12819125
12904583
14610273
14651853
14681479
15356189
15489334
15782199
16141072
16141073
16901643
17322295
17482317
17626619
18614015
18799693
19521500
21677750
22169199

Gene Ontology  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0006096  glycolysis
GO:0008152  metabolic process
GO:0006734  NADH metabolic process
GO:0055114  oxidation reduction
GO:0006104  succinyl-CoA metabolic process
GO:0006099  tricarboxylic acid cycle

Cellular Component

GO:0005739  mitochondrion
GO:0045252  oxoglutarate dehydrogenase complex

Molecular Function

GO:0051087  chaperone binding
GO:0031072  heat shock protein binding
GO:0016491  oxidoreductase activity
GO:0016624  oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0034602  oxoglutarate dehydrogenase (NAD+) activity
GO:0004591  oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0030976  thiamin pyrophosphate binding