profilin 2

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Synonym

Profilin II, Pfn2, profilin 2, Pfn, Profilin-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:170.20 cerebellum:55.30 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:172 spine:- retina:225 eye:76 artery/aorta:- vein:- lymphnode:21.60 peripheral blood:- spleen:26.30 thymus:9.90 bone marrow:- adipose:- bone:125.20 skin:87.10
GeneChip cerebrum:13.23 cerebellum:12.26 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:13.29 spine:13.13 retina:11.68 eye:10.91 artery/aorta:- vein:9.33 lymphnode:7.11 peripheral blood:- spleen:6.72 thymus:- bone marrow:4.70 adipose:10.42 bone:8.01 skin:10.18
CAGE cerebrum:5.26 cerebellum:- brain stem:5.71 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.77 retina:- eye:- artery/aorta:2.11 vein:- lymphnode:1.03 peripheral blood:- spleen:1.00 thymus:2.44 bone marrow:- adipose:- bone:2.72 skin:3.60
RNA-seq cerebrum:62.84 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:- prostate:92.60 ovary:23 testis:66.50 heart:74.40 muscle:35.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:20.10    bladder:- kidney:56.40 pituitary:51.70 thyroid/parathyroid:- adrenal gland:- pancreas:93.80 breast:6.50 salivary:-
GeneChip uterus:9.80 placenta:7.10 prostate:9.53 ovary:10.69 testis:10.88 heart:9.95 muscle:12.30 esophagus:- stomach:7.24 intestine:7.33 colon:- liver/hepato:6.03 lung:8.28 bladder:10.71 kidney:10.10 pituitary:11 thyroid/parathyroid:- adrenal gland:10.48 pancreas:7.86 breast:10.11 salivary:8.10
CAGE uterus:2.99 placenta:2.59 prostate:2.93 ovary:3.76 testis:5.59 heart:- muscle:- esophagus:- stomach:2.60 intestine:1.05 colon:1.40     liver/hepato:1.70    lung:2.29 bladder:3.76 kidney:- pituitary:3.73 thyroid/parathyroid:- adrenal gland:3.64 pancreas:1.30 breast:1.97 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:18.37 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_019410
Gene ID 18645
Unigene ID Mm.271744
Probe set ID 1418209_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027805

Orthologous Gene

Human[2]  NM_002628, NM_053024
Rat[1]  NM_030873, NM_053024

Chromosomal Region

-

Gene Family (Interpro ID)

IPR005454  Profilin, Mammalian
IPR002097  Profilin/allergen

Link to Pubmed  (Pubmed ID)

2717414
8449498
8889548
8975700
9463375
10349636
10945997
11027290
11034907
11042159
11076861
11217851
11274401
11826110
12466851
12477932
15489334
15615774
15751084
15782199
16141072
16141073
16319076
16716297
17374359
17541406
18001770
19497369
19554387
20937818
21267068
21920940
22081137
23153535

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0030837  negative regulation of actin filament polymerization
GO:0030838  positive regulation of actin filament polymerization
GO:0030833  regulation of actin filament polymerization

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0043195  terminal button

Molecular Function

GO:0003779  actin binding
GO:0005515  protein binding