ATP-binding cassette, sub-family B (MDR/TAP), member 1B

Synonym

Pgy-1, P-glycoprotein 1, Multidrug resistance protein 1, mdr, CD243 antigen, Mdr1, Pgy1, Mdr1b, Pgy1-1, Abcb1b, ATP-binding cassette sub-family B member 1, Abcb1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:6.90

cerebellum:-

brain stem:63.60

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:64.30

eye:-

artery/aorta:-

vein:-

lymphnode:10.80

peripheral blood:115

spleen:39.50

thymus:9.90

bone marrow:25.60

adipose:-

bone:-

skin:7.90

GeneChip

cerebrum:4.28

cerebellum:4.09

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.62

spine:4.32

retina:4.65

eye:6.21

artery/aorta:-

vein:4.93

lymphnode:5.67

peripheral blood:-

spleen:5.16

thymus:-

bone marrow:4.80

adipose:5.37

bone:6.42

skin:6.22

CAGE

cerebrum:1.38

cerebellum:-

brain stem:1.86

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.13

retina:-

eye:-

artery/aorta:3.60

vein:-

lymphnode:3.17

peripheral blood:-

spleen:2.04

thymus:1.75

bone marrow:-

adipose:-

bone:2.37

skin:2.79

RNA-seq

cerebrum:1.39

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:151.90

prostate:-

ovary:126.40

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:18.10

lung:10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:3.30

salivary:-

GeneChip

uterus:6.51

placenta:7.29

prostate:4.45

ovary:10.13

testis:4.53

heart:5.27

muscle:5.49

esophagus:-

stomach:4.34

intestine:4.31

colon:-

liver/hepato:4.57

lung:4.72

bladder:4.98

kidney:4.80

pituitary:4.52

thyroid/parathyroid:-

adrenal gland:12.94

pancreas:4.68

breast:5.34

salivary:4.72

CAGE

uterus:2.79

placenta:3.73

prostate:1.09

ovary:5.39

testis:0

heart:-

muscle:-

esophagus:-

stomach:0.67

intestine:1.60

colon:1.34

liver/hepato:0.91

lung:2.17

bladder:2.27

kidney:-

pituitary:1.69

thyroid/parathyroid:-

adrenal gland:7.20

pancreas:2.03

breast:1.08

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.42

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:5.43

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_011075
Gene ID	18669
Unigene ID	Mm.146649
Probe set ID	1418872_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028970

Orthologous Gene

Human[2]	NM_000927
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR017940	ABC transporter integral membrane type 1
IPR011527	ABC transporter, transmembrane domain, type 1
IPR003439	ABC transporter-like
IPR003593	ATPase, AAA+ type, core

Gene Ontology (GO ID)

Biological Process

GO:0006200	ATP catabolic process
GO:0015893	drug transport
GO:0014045	establishment of endothelial blood-brain barrier
GO:0008152	metabolic process
GO:0006855	multidrug transport
GO:0042493	response to drug
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0042908	xenobiotic transport

Cellular Component

GO:0016324	apical plasma membrane
GO:0000139	Golgi membrane
GO:0016021	integral to membrane
GO:0046581	intercellular canaliculus
GO:0016020	membrane
GO:0005739	mitochondrion
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances
GO:0015238	drug transporter activity
GO:0016787	hydrolase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0000166	nucleotide binding
GO:0005215	transporter activity
GO:0008559	xenobiotic-transporting ATPase activity

ATP-binding cassette, sub-family B (MDR/TAP), member 1B

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function