ATP-binding cassette, sub-family B (MDR/TAP), member 1A

Synonym

P-glycoprotein, MDR3, Abcb1a, MDR1A, ATP-binding cassette sub-family B member 1A, Pgp, Mdr1a, P-glycoprotein 3, Evi32, Abcb4, Pgy-3, Mdr3, P-gp, mdr-3, Multidrug resistance protein 3, multiple drug resistant 1a, Pgy3

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:7.60

artery/aorta:-

vein:-

lymphnode:21.60

peripheral blood:-

spleen:-

thymus:9.90

bone marrow:-

adipose:-

bone:-

skin:15.80

GeneChip

cerebrum:5.53

cerebellum:5.36

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.72

spine:5.80

retina:3.84

eye:5.39

artery/aorta:-

vein:3.47

lymphnode:5.02

peripheral blood:-

spleen:5.22

thymus:-

bone marrow:3.43

adipose:4.85

bone:3.90

skin:4.25

CAGE

cerebrum:0.41

cerebellum:-

brain stem:0.42

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.32

retina:-

eye:-

artery/aorta:1.40

vein:-

lymphnode:1.47

peripheral blood:-

spleen:0.86

thymus:0.27

bone marrow:-

adipose:-

bone:0.63

skin:0.51

RNA-seq

cerebrum:2.54

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:87.20

placenta:13.80

prostate:-

ovary:-

testis:14.80

heart:18.60

muscle:-

esophagus:-

stomach:-

intestine:628.50

colon:70.50

liver/hepato:-

lung:-

bladder:66.20

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:35.90

salivary:-

GeneChip

uterus:5.83

placenta:6.01

prostate:4.31

ovary:6.41

testis:3.75

heart:5.23

muscle:5.92

esophagus:-

stomach:9.62

intestine:9.73

colon:-

liver/hepato:3.61

lung:6.56

bladder:5.45

kidney:3.86

pituitary:3.59

thyroid/parathyroid:-

adrenal gland:6.13

pancreas:4.30

breast:4.76

salivary:3.89

CAGE

uterus:1.93

placenta:2.53

prostate:0.20

ovary:2.11

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:4.39

colon:5.40

liver/hepato:3.01

lung:1.38

bladder:0.68

kidney:-

pituitary:0.29

thyroid/parathyroid:-

adrenal gland:2.65

pancreas:0

breast:0.63

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.45

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:6.98

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_011076
Gene ID	18671
Unigene ID	Mm.207354
Probe set ID	1419758_at [Mouse430_2]
Ensembl ID	ENSMUSG00000040584

Orthologous Gene

Human[2]	NM_000927
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR017940	ABC transporter integral membrane type 1
IPR011527	ABC transporter, transmembrane domain, type 1
IPR003439	ABC transporter-like
IPR003593	ATPase, AAA+ type, core

Gene Ontology (GO ID)

Biological Process

GO:0006200	ATP catabolic process
GO:0015893	drug transport
GO:0000086	G2/M transition of mitotic cell cycle
GO:0008152	metabolic process
GO:0006855	multidrug transport
GO:0060548	negative regulation of cell death
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0042908	xenobiotic transport

Cellular Component

GO:0016324	apical plasma membrane
GO:0009986	cell surface
GO:0000139	Golgi membrane
GO:0016021	integral to membrane
GO:0046581	intercellular canaliculus
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0042623	ATPase activity, coupled
GO:0042626	ATPase activity, coupled to transmembrane movement of substances
GO:0016787	hydrolase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0000166	nucleotide binding
GO:0008559	xenobiotic-transporting ATPase activity

ATP-binding cassette, sub-family B (MDR/TAP), member 1A

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function