peroxisomal membrane protein 3

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Synonym

Peroxin-2, PMP35, Paf1, PEX2, peroxisomal membrane protein 3, Peroxisomal membrane protein 3, PAF-1, Pmp35, Pex2, Pxmp3, D3Ertd138e, Peroxisome assembly factor 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:57.30 cerebellum:18.40 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:95.50 spine:94.60 retina:32.10 eye:30.40 artery/aorta:84.40 vein:- lymphnode:43.20 peripheral blood:43.10 spleen:26.30 thymus:59.30 bone marrow:128.20 adipose:- bone:12.50 skin:47.50
GeneChip cerebrum:8.18 cerebellum:8.28 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.31 spine:8.54 retina:9.04 eye:8.56 artery/aorta:- vein:8.95 lymphnode:8.80 peripheral blood:- spleen:8.41 thymus:- bone marrow:8.43 adipose:9.63 bone:8.81 skin:8.77
CAGE cerebrum:2.99 cerebellum:- brain stem:3.24 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.30 retina:- eye:- artery/aorta:3.60 vein:- lymphnode:3.68 peripheral blood:- spleen:2.99 thymus:3.13 bone marrow:- adipose:- bone:3.25 skin:2.92
RNA-seq cerebrum:2.61 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:27.60 prostate:92.60 ovary:23 testis:29.60 heart:37.20 muscle:- esophagus:- stomach:- intestine:37 colon:88.10     liver/hepato:54.30        lung:120.50    bladder:- kidney:64.50 pituitary:77.50 thyroid/parathyroid:- adrenal gland:- pancreas:9.40 breast:58.80 salivary:-
GeneChip uterus:8.91 placenta:9.05 prostate:9.75 ovary:9.39 testis:7.40 heart:9.01 muscle:9.38 esophagus:- stomach:9.06 intestine:9.37 colon:- liver/hepato:9.88 lung:8.86 bladder:8.74 kidney:9.71 pituitary:8.80 thyroid/parathyroid:- adrenal gland:9.41 pancreas:8.76 breast:9.18 salivary:8.71
CAGE uterus:3.48 placenta:3.16 prostate:3.93 ovary:3.49 testis:2.30 heart:- muscle:- esophagus:- stomach:3.59 intestine:3.33 colon:3.67     liver/hepato:3.92    lung:3.30 bladder:3.28 kidney:- pituitary:3.39 thyroid/parathyroid:- adrenal gland:3.56 pancreas:3.74 breast:3.39 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:6.20 esophagus:- stomach:- intestine:- colon:-     liver/hepato:8.25        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001163301
Gene ID 19302
Unigene ID Mm.132336
Probe set ID 1420711_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000040374

Orthologous Gene

Human[4]  NM_000318, NM_001079867, NM_001172086, NM_001172087
Rat [0]  

Chromosomal Region

3A1  [5,560,188  -  5,576,239]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1546315
7551822
8043297
9382874
10349636
10464095
10504404
10725249
10922068
11042159
11076861
11161822
11217851
12466851
12477932
12746876
14673138
15618518
16141072
16141073
16919269
18287559
19110480
19521500
19830841
21267068
22441164

Gene Ontology  (GO ID)

Biological Process

GO:0006699  bile acid biosynthetic process
GO:0042632  cholesterol homeostasis
GO:0006635  fatty acid beta-oxidation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0048147  negative regulation of fibroblast proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007399  nervous system development
GO:0001764  neuron migration
GO:0007031  peroxisome organization
GO:0031648  protein destabilization
GO:0016558  protein import into peroxisome matrix
GO:0045540  regulation of cholesterol biosynthetic process
GO:0000038  very-long-chain fatty acid metabolic process

Cellular Component

GO:0016593  Cdc73/Paf1 complex
GO:0016021  integral to membrane
GO:0005779  integral to peroxisomal membrane
GO:0016020  membrane
GO:0005778  peroxisomal membrane
GO:0005777  peroxisome

Molecular Function

GO:0046872  metal ion binding
GO:0008270  zinc ion binding