roundabout homolog 1 (Drosophila)

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Synonym

DUTT1, roundabout homolog 1 (Drosophila), Roundabout homolog 1 precursor, AW742721, Dutt1, AW494633, Robo1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:67.70

cerebellum:36.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:189.10

retina:-

eye:22.80

artery/aorta:253.20

vein:-

lymphnode:-

peripheral blood:14.40

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:31.70

GeneChip

cerebrum:6.58

cerebellum:4.17

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.08

spine:6.75

retina:4.87

eye:6.18

artery/aorta:-

vein:6.29

lymphnode:5.39

peripheral blood:-

spleen:4.18

thymus:-

bone marrow:3.43

adipose:3.50

bone:4.29

skin:7.48

CAGE

cerebrum:2.66

cerebellum:-

brain stem:2.17

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.57

retina:-

eye:-

artery/aorta:0.95

vein:-

lymphnode:2.11

peripheral blood:-

spleen:1.00

thymus:1.95

bone marrow:-

adipose:-

bone:0.63

skin:3.63

RNA-seq

cerebrum:2.91

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:-

prostate:-

ovary:23

testis:81.30

heart:55.80

muscle:-

esophagus:-

stomach:229.10

intestine:-

colon:-

liver/hepato:-

lung:70.30

bladder:66.20

kidney:8.10

pituitary:12.90

thyroid/parathyroid:-

adrenal gland:424.40

pancreas:-

breast:-

salivary:-

GeneChip

uterus:6.67

placenta:4.39

prostate:4.95

ovary:6.80

testis:3.94

heart:3.89

muscle:4.07

esophagus:-

stomach:4.35

intestine:3.96

colon:-

liver/hepato:4.66

lung:5.51

bladder:5.62

kidney:3.04

pituitary:5.56

thyroid/parathyroid:-

adrenal gland:9.12

pancreas:3.68

breast:4.39

salivary:4.99

CAGE

uterus:3.50

placenta:1.87

prostate:1.23

ovary:3.40

testis:0.75

heart:-

muscle:-

esophagus:-

stomach:1.07

intestine:1.05

colon:1.03

liver/hepato:2.29

lung:2.61

bladder:2.88

kidney:-

pituitary:2.87

thyroid/parathyroid:-

adrenal gland:4.38

pancreas:1.30

breast:1.88

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.32

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.85

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_019413
Gene ID	19876
Unigene ID	Mm.310772
Probe set ID	1427231_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022883

Orthologous Gene

Human[3]	NM_001145845, NM_002941, NM_133631
Rat[1]	NM_022188, NM_002941, NM_133631

Chromosomal Region

Gene Family (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR013106	Immunoglobulin V-set
IPR003596	Immunoglobulin V-set, subgroup

Gene Ontology (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0007411	axon guidance
GO:0016199	axon midline choice point recognition
GO:0030154	cell differentiation
GO:0002042	cell migration involved in sprouting angiogenesis
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0006935	chemotaxis
GO:0007156	homophilic cell adhesion
GO:0060763	mammary duct terminal end bud growth
GO:0007275	multicellular organismal development
GO:0008285	negative regulation of cell proliferation
GO:0070100	negative regulation of chemokine-mediated signaling pathway
GO:0033600	negative regulation of mammary gland epithelial cell proliferation
GO:0050925	negative regulation of negative chemotaxis
GO:0007399	nervous system development
GO:0021891	olfactory bulb interneuron development
GO:0050772	positive regulation of axonogenesis
GO:0048814	regulation of dendrite morphogenesis

Cellular Component

GO:0030673	axolemma
GO:0030424	axon
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0016021	integral to membrane
GO:0016020	membrane

Molecular Function

GO:0008046	axon guidance receptor activity
GO:0042802	identical protein binding
GO:0030275	LRR domain binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity

roundabout homolog 1 (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function