sodium channel, voltage-gated, type V, alpha

jump to detail

Synonym

SkM1, mH1, sodium channel, voltage-gated, type V, alpha, Nav1.5, Nav1.5c, Scn5a

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:39.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:64.30

eye:15.20

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.06

cerebellum:5.13

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.02

spine:5.03

retina:4.87

eye:5.07

artery/aorta:-

vein:4.76

lymphnode:5.03

peripheral blood:-

spleen:4.99

thymus:-

bone marrow:4.91

adipose:5.10

bone:4.91

skin:4.85

CAGE

cerebrum:0.24

cerebellum:-

brain stem:0.78

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0.25

vein:-

lymphnode:1.20

peripheral blood:-

spleen:0.41

thymus:1.06

bone marrow:-

adipose:-

bone:0

skin:0.77

RNA-seq

cerebrum:3.30

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:13.80

prostate:-

ovary:-

testis:7.40

heart:55.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:3.30

salivary:-

GeneChip

uterus:4.78

placenta:5.03

prostate:5

ovary:4.76

testis:5.05

heart:8.18

muscle:5.07

esophagus:-

stomach:4.96

intestine:4.82

colon:-

liver/hepato:5.31

lung:4.90

bladder:4.89

kidney:4.84

pituitary:5.59

thyroid/parathyroid:-

adrenal gland:4.90

pancreas:5.56

breast:4.91

salivary:5.06

CAGE

uterus:0.31

placenta:1.48

prostate:0

ovary:0.45

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0.84

colon:0.23

liver/hepato:0

lung:0.91

bladder:0.18

kidney:-

pituitary:2.35

thyroid/parathyroid:-

adrenal gland:0

pancreas:0

breast:0.20

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:3.72

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_021544
Gene ID	20271
Unigene ID	Mm.103584
Probe set ID	1422194_at [Mouse430_2]
Ensembl ID	ENSMUSG00000032511

Orthologous Gene

Human[6]	NM_000335, NM_001099404, NM_001099405, NM_001160160, NM_001160161, NM_198056
Rat[2]	NM_001160162, NM_013125, NM_001099405, NM_001160160, NM_001160161, NM_198056

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0060048	cardiac muscle contraction
GO:0003231	cardiac ventricle development
GO:0071277	cellular response to calcium ion
GO:0006811	ion transport
GO:0051899	membrane depolarization
GO:0045760	positive regulation of action potential
GO:0050679	positive regulation of epithelial cell proliferation
GO:0010460	positive regulation of heart rate
GO:0010765	positive regulation of sodium ion transport
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization
GO:0060372	regulation of atrial cardiomyocyte membrane repolarization
GO:0002027	regulation of heart rate
GO:0034765	regulation of ion transmembrane transport
GO:0060373	regulation of ventricular cardiomyocyte membrane depolarization
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization
GO:0014894	response to denervation involved in regulation of muscle adaptation
GO:0014070	response to organic cyclic substance
GO:0006814	sodium ion transport
GO:0055085	transmembrane transport
GO:0006810	transport

Cellular Component

GO:0009986	cell surface
GO:0005783	endoplasmic reticulum
GO:0016021	integral to membrane
GO:0014704	intercalated disc
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0042383	sarcolemma
GO:0034706	sodium channel complex
GO:0030315	T-tubule
GO:0001518	voltage-gated sodium channel complex

Molecular Function

GO:0030506	ankyrin binding
GO:0005516	calmodulin binding
GO:0019899	enzyme binding
GO:0017134	fibroblast growth factor binding
GO:0005216	ion channel activity
GO:0005515	protein binding
GO:0005272	sodium channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005248	voltage-gated sodium channel activity

sodium channel, voltage-gated, type V, alpha

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function