solute carrier family 8 (sodium/calcium exchanger), member 1

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Synonym

Ncx1, Na(+)/Ca(2+)-exchange protein 1, Slc8a1, MGC90693, Sodium/calcium exchanger 1 precursor, D930008O12Rik, Ncx

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:59

cerebellum:36.80

brain stem:127.10

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:425.60

retina:32.10

eye:15.20

artery/aorta:84.40

vein:-

lymphnode:10.80

peripheral blood:28.80

spleen:-

thymus:29.60

bone marrow:-

adipose:-

bone:12.50

skin:-

GeneChip

cerebrum:4.03

cerebellum:4.18

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:3.67

spine:3.99

retina:3.72

eye:3.80

artery/aorta:-

vein:4.57

lymphnode:4.02

peripheral blood:-

spleen:4.21

thymus:-

bone marrow:4.16

adipose:3.75

bone:3.88

skin:3.72

CAGE

cerebrum:1.09

cerebellum:-

brain stem:0.29

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.17

retina:-

eye:-

artery/aorta:1.53

vein:-

lymphnode:0

peripheral blood:-

spleen:0.16

thymus:0.27

bone marrow:-

adipose:-

bone:0

skin:0

RNA-seq

cerebrum:2.41

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:30.90

ovary:11.50

testis:7.40

heart:409.20

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:27.20

lung:30.10

bladder:-

kidney:56.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:-

salivary:-

GeneChip

uterus:4.41

placenta:4.03

prostate:4.10

ovary:3.97

testis:4.06

heart:6.51

muscle:4

esophagus:-

stomach:4.20

intestine:4.26

colon:-

liver/hepato:4

lung:3.95

bladder:4.71

kidney:5.39

pituitary:4.01

thyroid/parathyroid:-

adrenal gland:3.66

pancreas:4.38

breast:3.87

salivary:4.02

CAGE

uterus:1.46

placenta:0.50

prostate:0.20

ovary:1.63

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:1.35

intestine:1.05

colon:0.82

liver/hepato:0

lung:1.59

bladder:4.15

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:0

pancreas:0

breast:0

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.64

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.68

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_011406
Gene ID	20541
Unigene ID	Mm.265834
Probe set ID	1425817_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000054640

Orthologous Gene

Human[36]	NM_001112800, NM_001112801, NM_001112802, NM_021097
Rat [0]

Chromosomal Region

17E3 [81,785,359 - 82,048,947]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004836	Sodium/calcium exchanger protein
IPR002987	Sodium/calcium exchanger, isoform 1

Gene Ontology (GO ID)

Biological Process

GO:0055074	calcium ion homeostasis
GO:0070509	calcium ion import
GO:0070588	calcium ion transmembrane transport
GO:0006816	calcium ion transport
GO:0060402	calcium ion transport into cytosol
GO:0055013	cardiac muscle cell development
GO:0060048	cardiac muscle contraction
GO:0007154	cell communication
GO:0006874	cellular calcium ion homeostasis
GO:0071313	cellular response to caffeine
GO:0071320	cellular response to cAMP
GO:0034614	cellular response to reactive oxygen species
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0035050	embryonic heart tube development
GO:0001892	embryonic placenta development
GO:0003007	heart morphogenesis
GO:0006811	ion transport
GO:0048747	muscle fiber development
GO:0010763	positive regulation of fibroblast migration
GO:0009791	post-embryonic development
GO:0051481	reduction of cytosolic calcium ion concentration
GO:0051924	regulation of calcium ion transport
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0002027	regulation of heart rate
GO:0002028	regulation of sodium ion transport
GO:0002026	regulation of the force of heart contraction
GO:0033198	response to ATP
GO:0001666	response to hypoxia
GO:0071436	sodium ion export
GO:0006814	sodium ion transport
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0014829	vascular smooth muscle contraction

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0042995	cell projection
GO:0043198	dendritic shaft
GO:0043197	dendritic spine
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0014704	intercalated disc
GO:0016020	membrane
GO:0005874	microtubule
GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0042383	sarcolemma
GO:0030315	T-tubule
GO:0030018	Z disc

Molecular Function

GO:0030506	ankyrin binding
GO:0015297	antiporter activity
GO:0005432	calcium:sodium antiporter activity
GO:0005516	calmodulin binding
GO:0008092	cytoskeletal protein binding
GO:0046872	metal ion binding
GO:0005515	protein binding

solute carrier family 8 (sodium/calcium exchanger), member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function