serine (or cysteine) peptidase inhibitor, clade B, member 6a

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Synonym

Serpinb6, Placental thrombin inhibitor, Serpin B6, AI876477, Spi3, Serpinb6a, PI-6, Protease inhibitor 6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:45.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:133.80 spine:94.60 retina:225 eye:91.20 artery/aorta:168.80 vein:- lymphnode:64.80 peripheral blood:43.10 spleen:118.50 thymus:9.90 bone marrow:166.70 adipose:212.70 bone:175.30 skin:87.10
GeneChip cerebrum:8.87 cerebellum:8.51 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:13.08 spine:9.67 retina:8.68 eye:9.90 artery/aorta:- vein:12.29 lymphnode:10.61 peripheral blood:- spleen:10.73 thymus:- bone marrow:9.97 adipose:10.88 bone:10.41 skin:12.42
CAGE cerebrum:3.41 cerebellum:- brain stem:3.56 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.88 retina:- eye:- artery/aorta:4.24 vein:- lymphnode:4.13 peripheral blood:- spleen:4.18 thymus:3.97 bone marrow:- adipose:- bone:3.99 skin:5.48
RNA-seq cerebrum:20.69 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:400.40 prostate:247.10 ovary:91.90 testis:133 heart:186 muscle:248.60 esophagus:- stomach:65.50 intestine:73.90 colon:229.10     liver/hepato:90.50        lung:150.60    bladder:66.20 kidney:8.10 pituitary:25.80 thyroid/parathyroid:337.40 adrenal gland:- pancreas:150.10 breast:104.50 salivary:216
GeneChip uterus:11.02 placenta:11.49 prostate:12.66 ovary:12.21 testis:11.19 heart:10.45 muscle:12.10 esophagus:- stomach:11.48 intestine:12.62 colon:- liver/hepato:8.39 lung:11.43 bladder:11.57 kidney:8.70 pituitary:10.54 thyroid/parathyroid:- adrenal gland:11.03 pancreas:10.43 breast:11.11 salivary:11.13
CAGE uterus:4.68 placenta:5.33 prostate:5.39 ovary:5.45 testis:5.71 heart:- muscle:- esophagus:- stomach:5.24 intestine:6.16 colon:6.40     liver/hepato:3.54    lung:4.93 bladder:5.24 kidney:- pituitary:4.61 thyroid/parathyroid:- adrenal gland:5.48 pancreas:4.17 breast:3.86 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:107.56 esophagus:- stomach:- intestine:- colon:-     liver/hepato:4.15        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001164118
Gene ID 20719
Unigene ID Mm.252210
Probe set ID 1450138_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000060147

Orthologous Gene

Human[1]  NM_001195291, NM_004568
Rat[2]  NM_001012214, NM_199085

Chromosomal Region

13A3.3  [34,009,787  -  34,094,663]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7608171
9174240
9182575
9321480
9832456
9875564
9892740
10349636
10856884
10922068
11042159
11076861
11217851
11641716
11863365
12466851
12477932
12638128
12872246
14610273
15082799
15489334
15782199
16141072
16141073
16175637
16919269
17761692
18799693
20451170
21267068
23669344
24172014

Gene Ontology  (GO ID)

Biological Process

GO:0008406  gonad development
GO:0010951  negative regulation of endopeptidase activity
GO:0010466  negative regulation of peptidase activity
GO:0030162  regulation of proteolysis

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0005622  intracellular
GO:0043234  protein complex

Molecular Function

GO:0030414  peptidase inhibitor activity
GO:0002020  protease binding
GO:0005515  protein binding
GO:0004867  serine-type endopeptidase inhibitor activity