myosin regulatory light chain interacting protein

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Synonym

Mylip, MGC11702, myosin regulatory light chain interacting protein, MIR, Ubiquitin ligase MYLIP, Myosin regulatory light chain-interacting protein, 9430057C20Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.60 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:172 spine:- retina:- eye:15.20 artery/aorta:168.80 vein:- lymphnode:129.60 peripheral blood:14.40 spleen:316 thymus:39.50 bone marrow:12.80 adipose:- bone:75.10 skin:7.90
GeneChip cerebrum:8.24 cerebellum:8.19 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.90 spine:7.51 retina:9.21 eye:10.04 artery/aorta:- vein:8.95 lymphnode:11.44 peripheral blood:- spleen:10.81 thymus:- bone marrow:10.49 adipose:9.57 bone:10.40 skin:9.75
CAGE cerebrum:3.09 cerebellum:- brain stem:2.66 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.83 retina:- eye:- artery/aorta:3.84 vein:- lymphnode:4.98 peripheral blood:- spleen:4.05 thymus:4.28 bone marrow:- adipose:- bone:4.20 skin:4.21
RNA-seq cerebrum:2.39 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:110.50 prostate:92.60 ovary:- testis:- heart:111.60 muscle:- esophagus:- stomach:- intestine:73.90 colon:-     liver/hepato:-        lung:40.20    bladder:- kidney:16.10 pituitary:180.80 thyroid/parathyroid:- adrenal gland:- pancreas:56.30 breast:45.70 salivary:108
GeneChip uterus:9.77 placenta:10.39 prostate:11.27 ovary:9.24 testis:5.99 heart:8.72 muscle:8.49 esophagus:- stomach:7.87 intestine:8.16 colon:- liver/hepato:8.39 lung:9 bladder:10.78 kidney:9.44 pituitary:8.36 thyroid/parathyroid:- adrenal gland:7.83 pancreas:8.78 breast:9.71 salivary:9.84
CAGE uterus:3.71 placenta:3.44 prostate:3.95 ovary:3.27 testis:1.34 heart:- muscle:- esophagus:- stomach:2.66 intestine:1.22 colon:3.00     liver/hepato:3.16    lung:3.70 bladder:4.68 kidney:- pituitary:3.21 thyroid/parathyroid:- adrenal gland:3.11 pancreas:3.64 breast:3.77 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.54 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.56        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_181043
Gene ID 218203
Unigene ID Mm.212855
Probe set ID 1424988_at  [Mouse430_2]
Ensembl ID ENSMUSG00000038175

Orthologous Gene

Human[1]  NM_013262
Rat [0]  

Chromosomal Region

13A5  [45,485,111  -  45,507,388]

Gene Family (Interpro ID)

IPR019749  Band 4.1 domain
IPR019750  Band 4.1 subgroup
IPR000798  Ezrin/radixin/moesin ERM

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
12466851
12477932
14651927
14681479
15489334
15782199
16141072
16141073
19520913
20427281
20562239
21343340
22109552
22261164
23382078

Gene Ontology  (GO ID)

Biological Process

GO:0006928  cellular component movement
GO:0042632  cholesterol homeostasis
GO:0010989  negative regulation of low-density lipoprotein particle clearance
GO:0007399  nervous system development
GO:0045732  positive regulation of protein catabolic process
GO:0031648  protein destabilization
GO:0016567  protein ubiquitination
GO:0042787  protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0032803  regulation of low-density lipoprotein receptor catabolic process
GO:0055098  response to low-density lipoprotein stimulus

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0019898  extrinsic to membrane
GO:0005622  intracellular
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0008092  cytoskeletal protein binding
GO:0016874  ligase activity
GO:0046872  metal ion binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding