pyrimidinergic receptor P2Y, G-protein coupled, 6

 jump to detail

Synonym

P2ry6, P2Y6, P2Y purinoceptor 6, pyrimidinergic receptor P2Y, G-protein coupled, 6, 2010204J23Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:- retina:- eye:7.60 artery/aorta:- vein:- lymphnode:54 peripheral blood:- spleen:26.30 thymus:9.90 bone marrow:51.30 adipose:- bone:25 skin:-
GeneChip cerebrum:4.79 cerebellum:4.35 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.23 spine:4.62 retina:4.64 eye:4.85 artery/aorta:- vein:6.49 lymphnode:8.14 peripheral blood:- spleen:6.96 thymus:- bone marrow:6.47 adipose:6.17 bone:6.24 skin:4.48
CAGE cerebrum:1.37 cerebellum:- brain stem:1.39 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.66 retina:- eye:- artery/aorta:2.68 vein:- lymphnode:3.95 peripheral blood:- spleen:1.99 thymus:2.22 bone marrow:- adipose:- bone:2.59 skin:2.19
RNA-seq cerebrum:0.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:73.90 colon:-     liver/hepato:-        lung:10    bladder:- kidney:- pituitary:- thyroid/parathyroid:112.50 adrenal gland:- pancreas:28.10 breast:29.40 salivary:-
GeneChip uterus:6.57 placenta:4.89 prostate:5.50 ovary:6.48 testis:4.88 heart:6.04 muscle:5.69 esophagus:- stomach:5.52 intestine:7.09 colon:- liver/hepato:4.97 lung:7.12 bladder:6.51 kidney:4.91 pituitary:4.70 thyroid/parathyroid:- adrenal gland:5.83 pancreas:5.90 breast:5.90 salivary:5.62
CAGE uterus:2.50 placenta:0.85 prostate:0.93 ovary:2.25 testis:0.45 heart:- muscle:- esophagus:- stomach:2.44 intestine:1.88 colon:2.07     liver/hepato:2.02    lung:2.77 bladder:2.70 kidney:- pituitary:1.22 thyroid/parathyroid:- adrenal gland:2.89 pancreas:1.84 breast:2.33 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.87 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.58        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_183168
Gene ID 233571
Unigene ID Mm.235193
Probe set ID 1425214_at  [Mouse430_2]
Ensembl ID ENSMUSG00000048779

Orthologous Gene

Human[4]  NM_004154, NM_176796, NM_176797, NM_176798
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR002286  P2 purinoceptor
IPR000371  P2Y3 purinoceptor
IPR001973  P2Y6 purinoceptor

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
11259526
12466851
12477932
15489334
15670583
16141072
16141073
16602821
17410128
18250478
18523137
19124756
19426712
20050854
20630102
21173118
21237152
21267068
21413988
21444765
21724990
21828185
22102722
23362118

Gene Ontology  (GO ID)

Biological Process

GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0014911  positive regulation of smooth muscle cell migration
GO:0007165  signal transduction
GO:0030321  transepithelial chloride transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004930  G-protein coupled receptor activity
GO:0045028  purinergic nucleotide receptor activity, G-protein coupled
GO:0019103  pyrimidine nucleotide binding
GO:0004871  signal transducer activity
GO:0045029  UDP-activated nucleotide receptor activity