dedicator of cytokinesis 4

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Synonym

C030023J22, 5330406C03, 6330411N01Rik, dedicator of cytokinesis 4, Dedicator of cytokinesis protein 4, EST N28122, Dock4, Kiaa0716, mKIAA0716, AF263288

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:4.71 cerebellum:- brain stem:3.58 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.37 retina:- eye:- artery/aorta:2.84 vein:- lymphnode:2.52 peripheral blood:- spleen:2.51 thymus:1.43 bone marrow:- adipose:- bone:1.97 skin:2.82
RNA-seq cerebrum:4.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:2.63 placenta:1.85 prostate:1.80 ovary:3.52 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:1.29 colon:1.89     liver/hepato:3.55    lung:4.12 bladder:2.56 kidney:- pituitary:3.51 thyroid/parathyroid:- adrenal gland:3.00 pancreas:2.33 breast:2.02 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.29 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.97        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_172803
Gene ID 238130
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000035954

Orthologous Gene

Human[1]  NM_014705
Rat[1]  NM_014705

Chromosomal Region

12B1  [41,172,640  -  41,573,073]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
10810084
10922068
11042159
11076861
11217851
12466851
12477932
12520002
12628187
12693553
14610273
15793261
16141072
16141073
16464467
16602821
19528233
19884258
21267068
23720743

Gene Ontology  (GO ID)

Biological Process

GO:0060326  cell chemotaxis
GO:0032855  positive regulation of Rac GTPase activity
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0032420  stereocilium
GO:0032421  stereocilium bundle

Molecular Function

GO:0005085  guanyl-nucleotide exchange factor activity
GO:0030165  PDZ domain binding
GO:0030675  Rac GTPase activator activity
GO:0048365  Rac GTPase binding
GO:0030971  receptor tyrosine kinase binding
GO:0017124  SH3 domain binding