HCLS1 associated X-1

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Synonym

Silg111, HAX-1, mHAX-1s, HCLS1 associated X-1, HS1-associating protein X-1, SIG-111, Hs1bp1, HS1-binding protein, Hax1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:78.10 cerebellum:- brain stem:190.70 corpus callosum/glia:- pineal gland:- peripheral nerve:76.40 spine:- retina:225 eye:30.40 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:14.40 spleen:13.20 thymus:59.30 bone marrow:141 adipose:- bone:137.80 skin:190
GeneChip cerebrum:11.24 cerebellum:11.21 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.94 spine:11.46 retina:11.10 eye:11.20 artery/aorta:- vein:11.05 lymphnode:11.09 peripheral blood:- spleen:10.93 thymus:- bone marrow:11.27 adipose:11.27 bone:11.17 skin:11.08
CAGE cerebrum:4.08 cerebellum:- brain stem:4.40 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.45 retina:- eye:- artery/aorta:4.11 vein:- lymphnode:3.91 peripheral blood:- spleen:4.15 thymus:4.05 bone marrow:- adipose:- bone:4.05 skin:4.06
RNA-seq cerebrum:13.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:82.80 prostate:30.90 ovary:68.90 testis:133 heart:37.20 muscle:106.50 esophagus:- stomach:32.70 intestine:147.90 colon:-     liver/hepato:117.70        lung:100.40    bladder:- kidney:40.30 pituitary:142.10 thyroid/parathyroid:224.90 adrenal gland:- pancreas:84.40 breast:52.20 salivary:108
GeneChip uterus:11.19 placenta:11.17 prostate:11.32 ovary:11.77 testis:11.12 heart:10.76 muscle:11.14 esophagus:- stomach:11.04 intestine:11.03 colon:- liver/hepato:12.05 lung:11.20 bladder:11.49 kidney:12.14 pituitary:12.03 thyroid/parathyroid:- adrenal gland:12.07 pancreas:10.65 breast:11.20 salivary:10.40
CAGE uterus:3.90 placenta:4.33 prostate:4.46 ovary:4.05 testis:4.65 heart:- muscle:- esophagus:- stomach:4.41 intestine:3.96 colon:4.05     liver/hepato:4.61    lung:3.92 bladder:4.08 kidney:- pituitary:4.32 thyroid/parathyroid:- adrenal gland:4.39 pancreas:4.77 breast:4.02 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:10.21 esophagus:- stomach:- intestine:- colon:-     liver/hepato:19.71        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_011826
Gene ID 23897
Unigene ID Mm.256035
Probe set ID 1438180_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027944

Orthologous Gene

Human[2]  NM_001018837, NM_006118
Rat[2]  NM_001018837, NM_006118

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7868883
7868905
8889548
9058808
10349636
10760273
10922068
11042159
11076861
11217851
12353922
12466851
12477932
14595844
14610273
14651853
15102471
15339924
15489334
16141072
16141073
16602821
16814492
16818771
17241641
18288109
18472110
18799693
19680265
19913549
19920172
20865787
22057932
22982986
23262083

Gene Ontology  (GO ID)

Biological Process

GO:0007166  cell surface receptor linked signal transduction
GO:0071345  cellular response to cytokine stimulus
GO:0030854  positive regulation of granulocyte differentiation
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030833  regulation of actin filament polymerization

Cellular Component

GO:0015629  actin cytoskeleton
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005783  endoplasmic reticulum
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0016529  sarcoplasmic reticulum
GO:0005667  transcription factor complex

Molecular Function

GO:0019966  interleukin-1 binding
GO:0005515  protein binding
GO:0047485  protein N-terminus binding