eukaryotic translation initiation factor 5A

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Synonym

eIF-4D, MGC6725, eIF-5A1, D19Wsu54e, eukaryotic translation initiation factor 5A, AA410058, eIF-5A-1, eIF-5A, Eif4d, Eukaryotic translation initiation factor 5A-1, Eukaryotic initiation factor 5A isoform 1, Eif5a

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:31.30 cerebellum:18.40 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:32.10 eye:38 artery/aorta:- vein:- lymphnode:43.20 peripheral blood:143.80 spleen:118.50 thymus:49.40 bone marrow:25.60 adipose:212.70 bone:75.10 skin:55.40
GeneChip cerebrum:12.64 cerebellum:12.48 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:12.82 spine:12.37 retina:11.06 eye:11.32 artery/aorta:- vein:12.84 lymphnode:13.12 peripheral blood:- spleen:12.95 thymus:- bone marrow:13.49 adipose:12.74 bone:13.18 skin:12.81
CAGE cerebrum:5.74 cerebellum:- brain stem:5.87 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.82 retina:- eye:- artery/aorta:6.09 vein:- lymphnode:5.90 peripheral blood:- spleen:6.43 thymus:6.25 bone marrow:- adipose:- bone:6.54 skin:6.04
RNA-seq cerebrum:95.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:30.90 ovary:57.50 testis:147.80 heart:37.20 muscle:106.50 esophagus:- stomach:163.60 intestine:73.90 colon:229.10     liver/hepato:81.50        lung:60.30    bladder:- kidney:64.50 pituitary:12.90 thyroid/parathyroid:112.50 adrenal gland:- pancreas:122 breast:62 salivary:-
GeneChip uterus:13.11 placenta:12.32 prostate:13.35 ovary:13.06 testis:12.93 heart:12.35 muscle:12.84 esophagus:- stomach:13.27 intestine:12.78 colon:- liver/hepato:12.98 lung:12.60 bladder:12.79 kidney:12.91 pituitary:12.94 thyroid/parathyroid:- adrenal gland:12.45 pancreas:12.65 breast:13.07 salivary:13.10
CAGE uterus:6.19 placenta:5.90 prostate:6.18 ovary:6.00 testis:7.04 heart:- muscle:- esophagus:- stomach:6.40 intestine:6.17 colon:6.16     liver/hepato:6.48    lung:5.76 bladder:5.87 kidney:- pituitary:5.83 thyroid/parathyroid:- adrenal gland:5.92 pancreas:6.65 breast:6.55 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:54.28 esophagus:- stomach:- intestine:- colon:-     liver/hepato:78.98        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001166596
Gene ID 276770
Unigene ID Mm.18026
Probe set ID 1451470_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000078812

Orthologous Gene

Human[14]  NM_001143760, NM_001143761, NM_001143762, NM_001970, NM_001099692
Rat[1]  NM_001033681, NM_001143761, NM_001143762, NM_001970, NM_001099692

Chromosomal Region

11B3  [69,730,216  -  69,735,460]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
9811942
10349636
10725249
10922068
11042159
11076861
11161802
11217851
12210765
12466851
12477932
12520002
12894223
12904583
14610273
15377278
15489334
15782199
16141072
16141073
16880268
17707773
18554416
18799693
20181941
20458750
20501948
21267068
21677750
21850436
22421546
23665500
24457600
24614889

Gene Ontology  (GO ID)

Biological Process

GO:0006917  induction of apoptosis
GO:0006406  mRNA export from nucleus
GO:0051028  mRNA transport
GO:0043066  negative regulation of apoptosis
GO:0008612  peptidyl-lysine modification to hypusine
GO:0043065  positive regulation of apoptosis
GO:0008284  positive regulation of cell proliferation
GO:0051149  positive regulation of muscle cell differentiation
GO:0045901  positive regulation of translational elongation
GO:0045905  positive regulation of translational termination
GO:0006611  protein export from nucleus
GO:0015031  protein transport
GO:0006412  translation
GO:0006414  translational elongation
GO:0006452  translational frameshifting
GO:0006810  transport

Cellular Component

GO:0005642  annulate lamellae
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0016020  membrane
GO:0005643  nuclear pore
GO:0005634  nucleus

Molecular Function

GO:0047485  protein N-terminus binding
GO:0043022  ribosome binding
GO:0003723  RNA binding
GO:0003746  translation elongation factor activity
GO:0017070  U6 snRNA binding