dehydrogenase/reductase (SDR family) member 4

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Synonym

D14Ucla2, Dhrs4, NADPH-dependent retinol dehydrogenase/reductase, RRD, mouNRDR, PHCR, AI043103, NDRD, dehydrogenase/reductase (SDR family) member 4, Dehydrogenase/reductase SDR family member 4, Peroxisomal short-chain alcohol dehydrogenase, AI790593

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:36.80 brain stem:95.30 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:14.40 spleen:- thymus:9.90 bone marrow:- adipose:- bone:12.50 skin:-
GeneChip cerebrum:6.43 cerebellum:7.11 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.10 spine:6.86 retina:5.13 eye:5.54 artery/aorta:- vein:7.57 lymphnode:7.56 peripheral blood:- spleen:6.99 thymus:- bone marrow:8.36 adipose:9.52 bone:7.72 skin:7.30
CAGE cerebrum:2.22 cerebellum:- brain stem:2.55 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.66 retina:- eye:- artery/aorta:4.11 vein:- lymphnode:2.54 peripheral blood:- spleen:3.17 thymus:2.91 bone marrow:- adipose:- bone:2.83 skin:3.17
RNA-seq cerebrum:3.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:11.50 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:8.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:28.10 breast:- salivary:-
GeneChip uterus:8.71 placenta:7.08 prostate:9.09 ovary:8.31 testis:8.11 heart:8.70 muscle:7.88 esophagus:- stomach:8.05 intestine:8.78 colon:- liver/hepato:10.60 lung:7.93 bladder:8.03 kidney:10.96 pituitary:6.88 thyroid/parathyroid:- adrenal gland:7.91 pancreas:7.24 breast:8.21 salivary:8.74
CAGE uterus:3.55 placenta:2.26 prostate:3.61 ovary:3.28 testis:3.78 heart:- muscle:- esophagus:- stomach:3.29 intestine:4.74 colon:4.28     liver/hepato:5.24    lung:2.74 bladder:3.37 kidney:- pituitary:2.01 thyroid/parathyroid:- adrenal gland:3.22 pancreas:3.04 breast:3.36 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:4.55 esophagus:- stomach:- intestine:- colon:-     liver/hepato:31.02        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001037938
Gene ID 28200
Unigene ID Mm.274277
Probe set ID 1419382_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022210

Orthologous Gene

Human[3]  NM_021004, NM_001193635, NM_001193636, NM_198083, NM_001082488
Rat[1]  NM_153315, NM_001193635, NM_001193636, NM_198083, NM_001082488

Chromosomal Region

14C3  [56,097,595  -  56,109,175]

Gene Family (Interpro ID)

IPR003560  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR002347  Glucose/ribitol dehydrogenase
IPR002424  Insect alcohol dehydrogenase family
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

8288233
8827514
8889548
10349636
11042159
11076861
11217851
12466851
12477932
12680773
14651853
15489334
15782199
16141072
16141073
16406282
17309103
18614015
20562862
23036705

Gene Ontology  (GO ID)

Biological Process

GO:0006066  alcohol metabolic process
GO:0042180  cellular ketone metabolic process
GO:0008152  metabolic process
GO:0055114  oxidation reduction
GO:0051262  protein tetramerization
GO:0042574  retinal metabolic process
GO:0008202  steroid metabolic process

Cellular Component

GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0005778  peroxisomal membrane
GO:0005777  peroxisome

Molecular Function

GO:0000253  3-keto sterol reductase activity
GO:0018455  alcohol dehydrogenase [NAD(P)+] activity
GO:0004090  carbonyl reductase (NADPH) activity
GO:0016491  oxidoreductase activity
GO:0016655  oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
GO:0005102  receptor binding
GO:0001758  retinal dehydrogenase activity