peroxiredoxin 5

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Synonym

peroxiredoxin 5, AOEB166, Prdx6, peroxiredoxin V, AOPP, Thioredoxin peroxidase PMP20, Peroxisomal antioxidant enzyme, Liver tissue 2D-page spot 2D-0014IV, PrxV, Thioredoxin reductase, Pmp20, Prdx5, Antioxidant enzyme B166, Peroxiredoxin-5, mitochondrial precursor, PMP20, Prx-V

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:173.70 cerebellum:55.30 brain stem:31.80 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:38.20 spine:- retina:96.40 eye:83.60 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:28.80 spleen:26.30 thymus:59.30 bone marrow:141 adipose:212.70 bone:112.70 skin:95
GeneChip cerebrum:10.55 cerebellum:10.92 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.85 spine:10.78 retina:9.28 eye:9.85 artery/aorta:- vein:10.45 lymphnode:10.31 peripheral blood:- spleen:9.47 thymus:- bone marrow:11.29 adipose:10.95 bone:11.18 skin:11.43
CAGE cerebrum:4.85 cerebellum:- brain stem:5.27 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.03 retina:- eye:- artery/aorta:5.03 vein:- lymphnode:3.30 peripheral blood:- spleen:3.97 thymus:3.80 bone marrow:- adipose:- bone:5.19 skin:5.06
RNA-seq cerebrum:110.68 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:261.70 placenta:151.90 prostate:185.30 ovary:34.50 testis:73.90 heart:167.40 muscle:497.10 esophagus:- stomach:65.50 intestine:517.60 colon:141     liver/hepato:253.40        lung:90.40    bladder:- kidney:475.50 pituitary:322.90 thyroid/parathyroid:899.80 adrenal gland:- pancreas:65.70 breast:75.10 salivary:162
GeneChip uterus:10.36 placenta:10.32 prostate:10.71 ovary:10.03 testis:9.89 heart:11.35 muscle:10.42 esophagus:- stomach:11.36 intestine:10.81 colon:- liver/hepato:11.21 lung:10 bladder:10.76 kidney:13.05 pituitary:10.24 thyroid/parathyroid:- adrenal gland:10.35 pancreas:9.25 breast:10.10 salivary:10.34
CAGE uterus:4.21 placenta:4.40 prostate:3.94 ovary:3.81 testis:5.05 heart:- muscle:- esophagus:- stomach:5.44 intestine:5.28 colon:5.49     liver/hepato:5.32    lung:4.30 bladder:4.76 kidney:- pituitary:4.37 thyroid/parathyroid:- adrenal gland:4.19 pancreas:3.99 breast:4.12 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:45.96 esophagus:- stomach:- intestine:- colon:-     liver/hepato:94.03        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_012021
Gene ID 54683
Unigene ID Mm.279782
Probe set ID 1416381_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000024953

Orthologous Gene

Human[3]  NM_012094, NM_181651, NM_181652
Rat[1]  NM_053610, NM_181651, NM_181652

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
10501973
10514471
10521424
10679306
10751410
10753630
10922068
11042159
11076861
11217851
11278957
12466851
12477932
12654475
12805289
14610273
14611647
14651853
14662316
15489334
15618518
15782199
15858817
16141072
16141073
16602821
18287559
18614015
19098005
20345759
21267068
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0034614  cellular response to reactive oxygen species
GO:0042744  hydrogen peroxide catabolic process
GO:0070995  NADPH oxidation
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0051354  negative regulation of oxidoreductase activity
GO:0016480  negative regulation of transcription from RNA polymerase III promoter
GO:0055114  oxidation reduction
GO:0032967  positive regulation of collagen biosynthetic process
GO:0060785  regulation of apoptosis involved in tissue homeostasis
GO:0006979  response to oxidative stress

Cellular Component

GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0043231  intracellular membrane-bounded organelle
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005782  peroxisomal matrix
GO:0005777  peroxisome

Molecular Function

GO:0016209  antioxidant activity
GO:0043027  caspase inhibitor activity
GO:0016491  oxidoreductase activity
GO:0004601  peroxidase activity
GO:0051920  peroxiredoxin activity
GO:0046983  protein dimerization activity
GO:0005102  receptor binding