meningioma expressed antigen 5 (hyaluronidase)

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Synonym

Mgea5, Ncoat, Meningioma-expressed antigen 5, mKIAA0679, Hexc, Hy5, Bifunctional protein NCOAT, 5830447M11Rik, AA408215, meningioma expressed antigen 5 (hyaluronidase), Kiaa0679, 2810009A20Rik, 4833427O07Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:13.20 thymus:39.50 bone marrow:- adipose:- bone:- skin:23.80
GeneChip cerebrum:11.77 cerebellum:11.33 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.25 spine:11.09 retina:11.43 eye:11.90 artery/aorta:- vein:10.89 lymphnode:11.47 peripheral blood:- spleen:11.33 thymus:- bone marrow:11.18 adipose:10.52 bone:11.32 skin:11.68
CAGE cerebrum:4.19 cerebellum:- brain stem:4.20 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.12 retina:- eye:- artery/aorta:3.26 vein:- lymphnode:3.58 peripheral blood:- spleen:3.94 thymus:4.81 bone marrow:- adipose:- bone:4.14 skin:3.97
RNA-seq cerebrum:11.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:30.90 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:3.30 salivary:-
GeneChip uterus:11.19 placenta:10.14 prostate:11.62 ovary:11.13 testis:8.89 heart:10.96 muscle:10.28 esophagus:- stomach:10.64 intestine:10.90 colon:- liver/hepato:9.95 lung:10.97 bladder:11.08 kidney:10.72 pituitary:11.06 thyroid/parathyroid:- adrenal gland:11.25 pancreas:10.41 breast:10.76 salivary:11
CAGE uterus:3.97 placenta:3.69 prostate:3.96 ovary:3.82 testis:3.77 heart:- muscle:- esophagus:- stomach:2.79 intestine:3.39 colon:3.55     liver/hepato:3.71    lung:3.93 bladder:3.83 kidney:- pituitary:3.70 thyroid/parathyroid:- adrenal gland:3.87 pancreas:4.06 breast:3.79 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:3.24 esophagus:- stomach:- intestine:- colon:-     liver/hepato:4.01        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_023799
Gene ID 76055
Unigene ID Mm.440640
Probe set ID 1433654_at  [Mouse430_2]
Ensembl ID ENSMUSG00000025220

Orthologous Gene

Human[4]  NM_001142434, NM_012215
Rat[1]  NM_131904, NM_012215

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
11341771
12466851
12477932
12520002
14610273
14621295
15226823
15345747
15485860
15489334
16141072
16141073
16356930
16376298
16397882
16505006
16517082
16602821
18799693
21267068
22056510
23453598

Gene Ontology  (GO ID)

Biological Process

GO:0046060  dATP metabolic process
GO:0016573  histone acetylation
GO:0008152  metabolic process
GO:0006044  N-acetylglucosamine metabolic process
GO:0070265  necrotic cell death
GO:0010616  negative regulation of cardiac muscle adaptation
GO:0060051  negative regulation of protein amino acid glycosylation
GO:0051928  positive regulation of calcium ion transport
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0031343  positive regulation of cell killing
GO:0051054  positive regulation of DNA metabolic process
GO:0046326  positive regulation of glucose import
GO:0060124  positive regulation of growth hormone secretion
GO:0032024  positive regulation of insulin secretion
GO:0051901  positive regulation of mitochondrial depolarization
GO:0043243  positive regulation of protein complex disassembly
GO:0045862  positive regulation of proteolysis
GO:0006612  protein targeting to membrane

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0016231  beta-N-acetylglucosaminidase activity
GO:0003824  catalytic activity
GO:0004402  histone acetyltransferase activity
GO:0016787  hydrolase activity
GO:0016798  hydrolase activity, acting on glycosyl bonds
GO:0016740  transferase activity
GO:0016746  transferase activity, transferring acyl groups