v-raf murine sarcoma viral oncogene homolog B1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:79.60 prostate:38 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_231692
Gene ID 114486
Unigene ID Rn.205813
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

4q22  [67,117,759  -  67,243,058]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

9679960
10336669
10648842
10854065
11707776
11719459
12650640
15150271
15782137
15886202
15917294
16157584
16424035
16474404
16508002
16818623
17126425
17310240
17380122
18060073
18098337
18194435
19079609
19289622
19720729
19955937
20951313
21203559
21277552
22177953

Gene Ontology  (GO ID)

Biological Process

GO:0000186  activation of MAPKK activity
GO:0071277  cellular response to calcium ion
GO:0000165  MAPKKK cascade
GO:0043066  negative regulation of apoptosis
GO:0043524  negative regulation of neuron apoptosis
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0010628  positive regulation of gene expression
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0051291  protein heterooligomerization
GO:0051591  response to cAMP
GO:0070849  response to epidermal growth factor stimulus
GO:0043434  response to peptide hormone stimulus

Cellular Component

GO:0005737  cytoplasm
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005509  calcium ion binding
GO:0004709  MAP kinase kinase kinase activity
GO:0046872  metal ion binding
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity