hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:122.90 bone marrow:- adipose:147.20 bone:- skin:-
GeneChip cerebrum:7.08 cerebellum:7.24 brain stem:7.50 corpus callosum/glia:- pineal gland:- peripheral nerve:7.08 spine:- retina:- eye:7.59 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.87 thymus:6.98 bone marrow:7.42 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:75.90 ovary:114.10 testis:82.30 heart:38.80 muscle:- esophagus:- stomach:- intestine:209.30 colon:-     liver/hepato:13.30        lung:101.30    bladder:- kidney:191.40 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:8.62 muscle:7.84 esophagus:- stomach:- intestine:7.42 colon:6.88 liver/hepato:- lung:- bladder:- kidney:6.91 pituitary:6.77 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_130826
Gene ID 170670
Unigene ID Rn.34751
Probe set ID X98225_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000024629

Orthologous Gene

Human[3]  NM_000182
Mouse[1]  NM_178878

Chromosomal Region

6q14  [26,173,798  -  26,191,435]

Gene Family (Interpro ID)

IPR002347  Glucose/ribitol dehydrogenase
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

1730633
7846063
8253773
9208944
10816122
11124150
12176671
12477932
18640292
20132223
23106098

Gene Ontology  (GO ID)

Biological Process

GO:0006635  fatty acid beta-oxidation
GO:0055114  oxidation reduction
GO:0042493  response to drug
GO:0032868  response to insulin stimulus

Cellular Component

GO:0005737  cytoplasm
GO:0016507  fatty acid beta-oxidation multienzyme complex
GO:0005743  mitochondrial inner membrane
GO:0042645  mitochondrial nucleoid
GO:0005739  mitochondrion
GO:0005730  nucleolus

Molecular Function

GO:0003857  3-hydroxyacyl-CoA dehydrogenase activity
GO:0003988  acetyl-CoA C-acyltransferase activity
GO:0000062  acyl-CoA binding
GO:0004300  enoyl-CoA hydratase activity
GO:0016509  long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0016508  long-chain-enoyl-CoA hydratase activity
GO:0051287  NAD or NADH binding
GO:0032403  protein complex binding