alcohol dehydrogenase 1 (class I)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.57 cerebellum:6.44 brain stem:6.80 corpus callosum/glia:- pineal gland:- peripheral nerve:6.15 spine:- retina:- eye:7.14 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.68 thymus:6.58 bone marrow:6.85 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:79.60 prostate:75.90 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:628 colon:289.90     liver/hepato:1675.40        lung:101.30    bladder:- kidney:510.50 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.78 muscle:6.54 esophagus:- stomach:- intestine:7.30 colon:10.20 liver/hepato:- lung:- bladder:- kidney:8.05 pituitary:7.23 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_019286
Gene ID 24172
Unigene ID Rn.40222
Probe set ID M15327_at  [RG_U34A]
Ensembl ID ENSRNOG00000012464

Orthologous Gene

Human[4]  NM_000667, NM_000668
Mouse[2]  NM_007409, NM_000668

Chromosomal Region

2q44  [235,799,457  -  235,811,584]

Gene Family (Interpro ID)

IPR013154  Alcohol dehydrogenase GroES-like
IPR013149  Alcohol dehydrogenase, zinc-binding
IPR011032  GroES-like
IPR016040  NAD(P)-binding domain

Link to Pubmed  (Pubmed ID)

1558299
2591969
2881847
2940107
4673366
8344317
10094961
12213809
12477932
12631290
12759105
12787032
15123720
15489334
16109828
16385241
16421892
17126819
17257171
17488809
18219182
19068087
22214999

Gene Ontology  (GO ID)

Biological Process

GO:0046186  acetaldehyde biosynthetic process
GO:0048149  behavioral response to ethanol
GO:0009790  embryonic development
GO:0006068  ethanol catabolic process
GO:0006069  ethanol oxidation
GO:0031100  organ regeneration
GO:0055114  oxidation reduction
GO:0032570  response to progesterone stimulus
GO:0032526  response to retinoic acid
GO:0048545  response to steroid hormone stimulus
GO:0033574  response to testosterone stimulus
GO:0042573  retinoic acid metabolic process
GO:0001523  retinoid metabolic process
GO:0042572  retinol metabolic process

Cellular Component

GO:0005829  cytosol
GO:0005622  intracellular
GO:0005739  mitochondrion

Molecular Function

GO:0004022  alcohol dehydrogenase (NAD) activity
GO:0008144  drug binding
GO:0035276  ethanol binding
GO:0051287  NAD or NADH binding
GO:0016491  oxidoreductase activity
GO:0042803  protein homodimerization activity
GO:0004745  retinol dehydrogenase activity
GO:0008270  zinc ion binding