calcium/calmodulin-dependent protein kinase II beta

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:382.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:142.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:117.10 skin:-
GeneChip cerebrum:10.12 cerebellum:10.78 brain stem:9.36 corpus callosum/glia:- pineal gland:- peripheral nerve:10.05 spine:- retina:- eye:7.97 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.96 thymus:7.74 bone marrow:7.89 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:19.40 muscle:531.50 esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:398.30 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.57 muscle:8.45 esophagus:- stomach:- intestine:8.70 colon:7.63 liver/hepato:- lung:- bladder:- kidney:7.81 pituitary:8.50 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001042356
Gene ID 24245
Unigene ID Rn.9743
Probe set ID M16112_g_at  [RG_U34A]
Ensembl ID ENSRNOG00000004005

Orthologous Gene

Human[32]  NM_001220, NM_172078, NM_172079, NM_172080, NM_172081, NM_172082, NM_172083, NM_172084
Mouse[1]  NM_001174053, NM_001174054, NM_007595, NM_172080, NM_172081, NM_172082, NM_172083, NM_172084

Chromosomal Region

14q21  [86,632,711  -  86,721,281]

Gene Family (Interpro ID)

IPR020636  Calcium/calmodulin-dependent protein kinase-like
IPR002291  Phosphorylase kinase, gamma catalytic subunit
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

2549638
3470758
7821422
9755160
11264466
11597763
11889801
12234658
12873385
15312654
15576376
16436603
16928958
18562151
18840684
19047462
21610080
21718540
21725312
21952434
22114270
22334212
22579289
22717267
23352984
23990563

Gene Ontology  (GO ID)

Biological Process

GO:0060466  activation of meiosis involved in egg activation
GO:0006816  calcium ion transport
GO:0000082  G1/S transition of mitotic cell cycle
GO:0002030  inhibitory G-protein coupled receptor phosphorylation
GO:0060291  long-term synaptic potentiation
GO:0050885  neuromuscular process controlling balance
GO:0018105  peptidyl-serine phosphorylation
GO:0010976  positive regulation of neuron projection development
GO:0090129  positive regulation of synapse maturation
GO:0046777  protein amino acid autophosphorylation
GO:0048169  regulation of long-term neuronal synaptic plasticity
GO:0032222  regulation of synaptic transmission, cholinergic
GO:0046686  response to cadmium ion

Cellular Component

GO:0005954  calcium- and calmodulin-dependent protein kinase complex
GO:0005829  cytosol
GO:0005815  microtubule organizing center
GO:0033017  sarcoplasmic reticulum membrane
GO:0051233  spindle midzone

Molecular Function

GO:0005524  ATP binding
GO:0005516  calmodulin binding
GO:0004683  calmodulin-dependent protein kinase activity
GO:0005515  protein binding