cyclin-dependent kinase inhibitor 1C

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:215.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:- bone:195.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:2230.20 prostate:38 ovary:- testis:- heart:290.80 muscle:- esophagus:- stomach:- intestine:314 colon:-     liver/hepato:-        lung:152    bladder:1129.90 kidney:382.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001033757
Gene ID 246060
Unigene ID Rn.162507
Probe set ID -
Ensembl ID ENSRNOG00000020559

Orthologous Gene

Human[12]  NM_000076, NM_001122630, NM_001122631
Mouse[2]  NM_001161624, NM_009876, NM_001122631

Chromosomal Region

1q41  [203,835,228  -  203,837,562]

Gene Family (Interpro ID)

IPR003175  Cyclin-dependent kinase inhibitor

Link to Pubmed  (Pubmed ID)

11723059
12477932
12947022
14671317
16259944
17553990
18721488
18814313
19458044
19533683
19934273
21245411
22127597
22874918

Gene Ontology  (GO ID)

Biological Process

GO:0007050  cell cycle arrest
GO:0050680  negative regulation of epithelial cell proliferation
GO:0033673  negative regulation of kinase activity
GO:0042326  negative regulation of phosphorylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0042551  neuron maturation
GO:0001890  placenta development
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0004861  cyclin-dependent protein kinase inhibitor activity
GO:0016301  kinase activity
GO:0005515  protein binding