6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip cerebrum:7.23 cerebellum:6.86 brain stem:7.19 corpus callosum/glia:- pineal gland:- peripheral nerve:6.84 spine:- retina:- eye:7.53 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.82 thymus:6.92 bone marrow:7.05 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:- ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.07 muscle:7.09 esophagus:- stomach:- intestine:6.91 colon:6.82 liver/hepato:- lung:- bladder:- kidney:7.11 pituitary:6.92 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001033964
Gene ID 24640
Unigene ID Rn.44844
Probe set ID X65953mRNA_at  [RG_U34A]
Ensembl ID ENSRNOG00000004162

Orthologous Gene

Human[3]  NM_001018053, NM_006212
Mouse[7]  NM_001162415, NM_001162416, NM_008825

Chromosomal Region

13q13  [43,627,327  -  43,652,660]

Gene Family (Interpro ID)

IPR016260  Bifunctional 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-phosphatase
IPR003094  Fructose-2,6-bisphosphatase

Link to Pubmed  (Pubmed ID)

1299004
1652483
7612629
8292038
8814283
8889548
9716657
11401535
11522786
14623077
15170386
16980436
17553851
18039179
18199594
18710022
19140452
23457334

Gene Ontology  (GO ID)

Biological Process

GO:0006003  fructose 2,6-bisphosphate metabolic process
GO:0006000  fructose metabolic process
GO:0006007  glucose catabolic process
GO:0006096  glycolysis
GO:0006089  lactate metabolic process
GO:0033133  positive regulation of glucokinase activity
GO:0032024  positive regulation of insulin secretion
GO:0006090  pyruvate metabolic process
GO:0009749  response to glucose stimulus

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0003873  6-phosphofructo-2-kinase activity
GO:0005524  ATP binding
GO:0004331  fructose-2,6-bisphosphate 2-phosphatase activity
GO:0019900  kinase binding
GO:0019901  protein kinase binding