tumor necrosis factor (ligand) superfamily, member 10

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:114.10 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_145681
Gene ID 246775
Unigene ID Rn.83627
Probe set ID -
Ensembl ID ENSRNOG00000013269

Orthologous Gene

Human[3]  NM_001190942, NM_001190943, NM_003810
Mouse[1]  NM_009425, NM_001190943, NM_003810

Chromosomal Region

2q24  [113,204,304  -  113,221,548]

Gene Family (Interpro ID)

IPR006052  Tumor Necrosis Factor
IPR006053  Tumor necrosis factor alpha/beta/c
IPR008983  Tumour necrosis factor-like

Link to Pubmed  (Pubmed ID)

12021051
12573821
12577054
12882912
14872496
16178278
16313792
17000905
17352408
17403612
17627577
17641850
18057577
18287563
18362891
18649770
19385008
19572802
19961901
22286051
22520731
23274391

Gene Ontology  (GO ID)

Biological Process

GO:0006955  immune response
GO:0006917  induction of apoptosis
GO:0008584  male gonad development
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0032868  response to insulin stimulus

Cellular Component

GO:0005575  cellular_component
GO:0005615  extracellular space
GO:0016020  membrane

Molecular Function

GO:0005125  cytokine activity
GO:0003674  molecular_function
GO:0005164  tumor necrosis factor receptor binding
GO:0032813  tumor necrosis factor receptor superfamily binding