forkhead box A1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:106.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:- ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:26.60        lung:50.70    bladder:- kidney:63.80 pituitary:177.70 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_012742
Gene ID 25098
Unigene ID Rn.104707
Probe set ID -
Ensembl ID ENSRNOG00000009284

Orthologous Gene

Human[1]  NM_004496
Mouse[1]  NM_008259

Chromosomal Region

6q23  [78,005,334  -  78,009,176]

Gene Family (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

2227418
10024498
15060019
17220277
18003659
19649697

Gene Ontology  (GO ID)

Biological Process

GO:0060441  branching involved in lung morphogenesis
GO:0016568  chromatin modification
GO:0006338  chromatin remodeling
GO:0009790  embryonic development
GO:0060743  epithelial cell maturation involved in prostate gland development
GO:0060738  epithelial-mesenchymal signaling involved in prostate gland development
GO:0042593  glucose homeostasis
GO:0042445  hormone metabolic process
GO:0030324  lung development
GO:0060487  lung epithelial cell differentiation
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048665  neuron fate specification
GO:0007389  pattern specification process
GO:0033148  positive regulation of estrogen receptor signaling pathway
GO:0045931  positive regulation of mitotic cell cycle
GO:0045666  positive regulation of neuron differentiation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0060740  prostate gland epithelium morphogenesis
GO:0060741  prostate gland stromal morphogenesis
GO:0010468  regulation of gene expression
GO:0010817  regulation of hormone levels
GO:0051090  regulation of transcription factor activity
GO:0032355  response to estradiol stimulus
GO:0060528  secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0035239  tube morphogenesis

Cellular Component

GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0019904  protein domain specific binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding