calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:107.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:79.60 prostate:227.70 ovary:- testis:- heart:96.90 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:296.10 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_012918
Gene ID 25398
Unigene ID Rn.87769
Probe set ID -
Ensembl ID ENSRNOG00000002559

Orthologous Gene

Human[6]  NM_000068, NM_001127221, NM_001127222, NM_001174080, NM_023035
Mouse[1]  NM_007578, NM_001127221, NM_001127222, NM_001174080, NM_023035

Chromosomal Region

19q11  [25,188,220  -  25,424,495]

Gene Family (Interpro ID)

IPR020478  A.T hook-like
IPR017956  AT hook, DNA-binding motif
IPR002077  Voltage-dependent calcium channel, alpha-1 subunit
IPR005448  Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit
IPR003091  Voltage-dependent potassium channel

Link to Pubmed  (Pubmed ID)

1279681
1648226
1692134
9593738
10945665
11342703
11865310
12895521
14530926
14673106
15090043
15548655
15577901
15728831
15750602
15768038
15953418
15980432
16049183
16049184
16278278
16373336
16736476
16820014
16868246
17068255
17196942
17893194
18390553
18433788
18536931
19883739
20511524
21389298
21611731
21746798
22504905
22589533
22869375
24453334

Gene Ontology  (GO ID)

Biological Process

GO:0007628  adult walking behavior
GO:0048266  behavioral response to pain
GO:0070509  calcium ion import
GO:0070588  calcium ion transmembrane transport
GO:0006816  calcium ion transport
GO:0017156  calcium ion-dependent exocytosis
GO:0048791  calcium ion-dependent exocytosis of neurotransmitter
GO:0008219  cell death
GO:0016049  cell growth
GO:0030644  cellular chloride ion homeostasis
GO:0021953  central nervous system neuron differentiation
GO:0021679  cerebellar molecular layer development
GO:0021702  cerebellar Purkinje cell differentiation
GO:0021680  cerebellar Purkinje cell layer development
GO:0021590  cerebellum maturation
GO:0048813  dendrite morphogenesis
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0014051  gamma-aminobutyric acid secretion
GO:0007214  gamma-aminobutyric acid signaling pathway
GO:0006006  glucose metabolic process
GO:0042445  hormone metabolic process
GO:0051899  membrane depolarization
GO:0050883  musculoskeletal movement, spinal reflex action
GO:0032353  negative regulation of hormone biosynthetic process
GO:0043524  negative regulation of neuron apoptosis
GO:0007270  nerve-nerve synaptic transmission
GO:0050877  neurological system process
GO:0050905  neuromuscular process
GO:0050885  neuromuscular process controlling balance
GO:0007274  neuromuscular synaptic transmission
GO:0042133  neurotransmitter metabolic process
GO:0043113  receptor clustering
GO:0014056  regulation of acetylcholine secretion
GO:0050770  regulation of axonogenesis
GO:0017158  regulation of calcium ion-dependent exocytosis
GO:0042391  regulation of membrane potential
GO:0048265  response to pain
GO:0060024  rhythmic synaptic transmission
GO:0019233  sensory perception of pain
GO:0021522  spinal cord motor neuron differentiation
GO:0000096  sulfur amino acid metabolic process
GO:0007416  synapse assembly
GO:0007268  synaptic transmission
GO:0051932  synaptic transmission, GABAergic
GO:0035249  synaptic transmission, glutamatergic
GO:0042403  thyroid hormone metabolic process
GO:0019226  transmission of nerve impulse
GO:0021750  vestibular nucleus development

Cellular Component

GO:0042995  cell projection
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005634  nucleus
GO:0043204  perikaryon
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0005891  voltage-gated calcium channel complex

Molecular Function

GO:0005516  calmodulin binding
GO:0008331  high voltage-gated calcium channel activity
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0019905  syntaxin binding
GO:0005245  voltage-gated calcium channel activity