phosphatidylethanolamine N-methyltransferase

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:106.60 artery/aorta:357.10 vein:- lymphnode:- peripheral blood:- spleen:234 thymus:- bone marrow:- adipose:147.20 bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:238.90 prostate:227.70 ovary:228.20 testis:- heart:96.90 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:113.80 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013003
Gene ID 25511
Unigene ID Rn.98750
Probe set ID -
Ensembl ID ENSRNOG00000043216

Orthologous Gene

Human[3]  NM_007169, NM_148172, NM_148173
Mouse[1]  NM_008819, NM_148172, NM_148173

Chromosomal Region

10q22  [46,300,118  -  46,302,889]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7766014
7929120
8344945
8445336
9406167
9566595
12091487
12477932
12482759
16391469
16756957
17116711
17156888
17614848

Gene Ontology  (GO ID)

Biological Process

GO:0006650  glycerophospholipid metabolic process
GO:0008285  negative regulation of cell proliferation
GO:0006656  phosphatidylcholine biosynthetic process
GO:0006644  phospholipid metabolic process
GO:0050747  positive regulation of lipoprotein metabolic process
GO:0043200  response to amino acid stimulus
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0007584  response to nutrient
GO:0033273  response to vitamin
GO:0046498  S-adenosylhomocysteine metabolic process
GO:0046500  S-adenosylmethionine metabolic process

Cellular Component

GO:0031526  brush border membrane
GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0031966  mitochondrial membrane
GO:0042383  sarcolemma

Molecular Function

GO:0008170  N-methyltransferase activity
GO:0080101  phosphatidyl-N-dimethylethanolamine N-methyltransferase activity
GO:0000773  phosphatidyl-N-methylethanolamine N-methyltransferase activity
GO:0008429  phosphatidylethanolamine binding
GO:0004608  phosphatidylethanolamine N-methyltransferase activity
GO:0008757  S-adenosylmethionine-dependent methyltransferase activity