peroxisome proliferator-activated receptor gamma

jump to detail

Synonym

-

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:441.60 bone:- skin:-
GeneChip cerebrum:5.51 cerebellum:5.42 brain stem:5.78 corpus callosum/glia:- pineal gland:- peripheral nerve:5.71 spine:- retina:- eye:6.03 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.15 thymus:5.42 bone marrow:5.64 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:318.60 prostate:38 ovary:114.10 testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:418.70 colon:289.90     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.59 muscle:5.59 esophagus:- stomach:- intestine:5.89 colon:7.06 liver/hepato:- lung:- bladder:- kidney:5.44 pituitary:5.18 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

IDs

Refseq ID NM_001145366
Gene ID 25664
Unigene ID Rn.23443
Probe set ID AB011365_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000008839

Orthologous Gene

Human[4]  NM_005037, NM_015869, NM_138711, NM_138712
Mouse[2]  NM_001127330, NM_011146, NM_138711, NM_138712

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

8943212
8953045
9030579
9753710
9918859
10394368
10438514
10622252
10797535
11181544
11318962
11564675
11710539
11752099
11777901
11936221
11996104
12052825
12083418
12118251
12456800
12488352
12540599
12699904
12706490
12885795
12914523
12923396
12941763
12966092
14567501
14588098
14592449
14600076
14680975
14749268
14766236
14871416
15033806
15055257
15112352
15118671
15167281
15170673
15253107
15284449
15304320
15358182
15474499
15483210
15518707
15527799
15528772
15558556
15561927
15562025
15563986
15572034
15618443
15632188
15649892
15713687
15733374
15737646
15754086
15767042
15774612
15779851
15820709
15878969
15940641
15967870
15970297
15993383
16083301
16096283
16180333
16183630
16186413
16202214
16213464
16247333
16257923
16259921
16266488
16329595
16344371
16484294
16554032
16556873
16563274
16574311
16580578
16670091
16815847
16939881
16959952
17003342
17003451
17072978
17101152
17116814
17170230
17317771
17362636
17394460
17409529
17435078
17461532
17484875
17494862
17589386
17601490
17625041
17627264
17643263
17643887
17667812
17669705
17947702
17965419
17966466
17989144
18041089
18047631
18074385
18157544
18274641
18283099
18289512
18304850
18316027
18332871
18360056
18378216
18384703
18387855
18388116
18394743
18417957
18421861
18427128
18437150
18455351
18457007
18466197
18467141
18471812
18475159
18479673
18486259
18511847
18520050
18541841
18543250
18562038
18562925
18565023
18573313
18583255
18594976
18598350
18600431
18621767
18625072
18639367
18641696
18658087
18683148
18696335
18712722
18769493
18776709
18780770
18783396
18806296
18815186
18828195
18845632
18846335
18959602
18971352
18973594
19000376
19080338
19143008
19152448
19157823
19168033
19211718
19221220
19251397
19262292
19280879
19281808
19339015
19365232
19377624
19383491
19396032
19408657
19436234
19452630
19485965
19524138
19570670
19576043
19609456
19666838
19689083
19808645
19808779
19893245
19926821
19932685
19940035
19942298
19968884
20018750
20021832
20045920
20164119
20212046
20221786
20364582
20404217
20465636
20630681
20644547
20663865
20663893
20668686
20689342
20705243
20732852
20813360
20884641
20948513
20959535
21029595
21060836
21109018
21162229
21162800
21190014
21221986
21295034
21425435
21440907
21451213
21455100
21487070
21501116
21532595
21600121
21602449
21641970
21709632
21763752
21793336
21835234
21926264
21996045
22014456
22019459
22033706
22038624
22094441
22126757
22163051
22219595
22249025
22253423
22253428
22271545
22282354
22444276
22464285
22466807
22467681
22529699
22554584
22561360
22595559
22706027
22714093
22792090
22842585
22849356
22917842
23104384
23108648
23122950
23208382
23239524
23292098
23323617
23372643
23468969
23500012
23500774
23520555
23526219
23559865
23656243
23788637
23794089
23874818
24011919
24039778
24194635
24291733
24321547
24389592

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0050873  brown fat cell differentiation
GO:0045165  cell fate commitment
GO:0048469  cell maturation
GO:0032869  cellular response to insulin stimulus
GO:0071285  cellular response to lithium ion
GO:0071407  cellular response to organic cyclic substance
GO:0030855  epithelial cell differentiation
GO:0045444  fat cell differentiation
GO:0006631  fatty acid metabolic process
GO:0019395  fatty acid oxidation
GO:0042593  glucose homeostasis
GO:0007507  heart development
GO:0006917  induction of apoptosis
GO:0042953  lipoprotein transport
GO:0015909  long-chain fatty acid transport
GO:0045713  low-density lipoprotein receptor biosynthetic process
GO:0030224  monocyte differentiation
GO:0002674  negative regulation of acute inflammatory response
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010887  negative regulation of cholesterol storage
GO:0001818  negative regulation of cytokine production
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0010871  negative regulation of receptor biosynthetic process
GO:0010891  negative regulation of sequestering of triglyceride
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0051974  negative regulation of telomerase activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0031100  organ regeneration
GO:0001890  placenta development
GO:0045600  positive regulation of fat cell differentiation
GO:0046321  positive regulation of fatty acid oxidation
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0008217  regulation of blood pressure
GO:0045598  regulation of fat cell differentiation
GO:0019216  regulation of lipid metabolic process
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0031000  response to caffeine
GO:0009409  response to cold
GO:0042493  response to drug
GO:0043627  response to estrogen stimulus
GO:0033993  response to lipid
GO:0055098  response to low-density lipoprotein stimulus
GO:0014070  response to organic cyclic substance
GO:0010033  response to organic substance
GO:0032526  response to retinoic acid
GO:0033189  response to vitamin A
GO:0007165  signal transduction
GO:0050872  white fat cell differentiation

Cellular Component

GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0050544  arachidonic acid binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0008144  drug binding
GO:0019899  enzyme binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0005515  protein binding
GO:0046965  retinoid X receptor binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0033613  transcription activator binding
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding