sodium channel, voltage-gated, type V, alpha subunit

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.96 cerebellum:6.95 brain stem:7.16 corpus callosum/glia:- pineal gland:- peripheral nerve:7 spine:- retina:- eye:7.23 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.97 thymus:6.88 bone marrow:7.09 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.51 muscle:6.92 esophagus:- stomach:- intestine:6.85 colon:6.70 liver/hepato:- lung:- bladder:- kidney:6.89 pituitary:6.67 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013125
Gene ID 25665
Unigene ID -
Probe set ID M27902_at  [RG_U34A]
Ensembl ID ENSRNOG00000015049

Orthologous Gene

Human[6]  NM_000335, NM_001099404, NM_001099405, NM_001160160, NM_001160161, NM_198056
Mouse[1]  NM_021544, NM_001099404, NM_001099405, NM_001160160, NM_001160161, NM_198056

Chromosomal Region

8q32  [124,447,379  -  124,545,301]

Gene Family (Interpro ID)

IPR002077  Voltage-dependent calcium channel, alpha-1 subunit
IPR003091  Voltage-dependent potassium channel

Link to Pubmed  (Pubmed ID)

2554302
8889548
11238277
11786529
12208804
12401812
12562928
15047701
15060019
15579534
15840476
16115203
16331678
16966585
17259145
17900547
18032528
18180363
19376164
19471098
19584134
19661460
19745168
20517693
20724705
21164104
21640979
21677263
22331407
22336133
22811280
23091085
23684688

Gene Ontology  (GO ID)

Biological Process

GO:0003360  brainstem development
GO:0060048  cardiac muscle contraction
GO:0003231  cardiac ventricle development
GO:0071277  cellular response to calcium ion
GO:0021549  cerebellum development
GO:0051899  membrane depolarization
GO:0042475  odontogenesis of dentine-containing tooth
GO:0045760  positive regulation of action potential
GO:0050679  positive regulation of epithelial cell proliferation
GO:0010460  positive regulation of heart rate
GO:0010765  positive regulation of sodium ion transport
GO:0060371  regulation of atrial cardiomyocyte membrane depolarization
GO:0060372  regulation of atrial cardiomyocyte membrane repolarization
GO:0002027  regulation of heart rate
GO:0034765  regulation of ion transmembrane transport
GO:0060373  regulation of ventricular cardiomyocyte membrane depolarization
GO:0060307  regulation of ventricular cardiomyocyte membrane repolarization
GO:0014894  response to denervation involved in regulation of muscle adaptation
GO:0014070  response to organic cyclic substance
GO:0006814  sodium ion transport
GO:0021537  telencephalon development

Cellular Component

GO:0009986  cell surface
GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0014704  intercalated disc
GO:0005886  plasma membrane
GO:0042383  sarcolemma
GO:0034706  sodium channel complex
GO:0030315  T-tubule
GO:0001518  voltage-gated sodium channel complex

Molecular Function

GO:0030506  ankyrin binding
GO:0005516  calmodulin binding
GO:0019899  enzyme binding
GO:0017134  fibroblast growth factor binding
GO:0050998  nitric-oxide synthase binding
GO:0005515  protein binding
GO:0005248  voltage-gated sodium channel activity