phosphofructokinase, liver

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:179.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:142.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:122.90 bone marrow:- adipose:294.40 bone:156.20 skin:470.80
GeneChip cerebrum:7.66 cerebellum:7.29 brain stem:7.52 corpus callosum/glia:- pineal gland:- peripheral nerve:7.62 spine:- retina:- eye:7.24 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.16 thymus:7.47 bone marrow:7.74 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:278.80 prostate:113.90 ovary:- testis:- heart:116.30 muscle:- esophagus:- stomach:1077.60 intestine:- colon:-     liver/hepato:79.80        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.41 muscle:7.15 esophagus:- stomach:- intestine:7.47 colon:7.43 liver/hepato:- lung:- bladder:- kidney:7.45 pituitary:8.08 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013190
Gene ID 25741
Unigene ID Rn.4212
Probe set ID X58865mRNA_at  [RG_U34A]
Ensembl ID ENSRNOG00000001214

Orthologous Gene

Human[2]  NM_002626
Mouse[2]  NM_008826

Chromosomal Region

20p12  [11,009,349  -  11,032,513]

Gene Family (Interpro ID)

IPR000023  Phosphofructokinase

Link to Pubmed  (Pubmed ID)

156182
1834654
1836995
2931076
4273555
4353083
6240262
6446905
6458283
12477932
12482582
14342527
15060019
22871113

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0046835  carbohydrate phosphorylation
GO:0030388  fructose 1,6-bisphosphate metabolic process
GO:0006002  fructose 6-phosphate metabolic process
GO:0006096  glycolysis
GO:0046676  negative regulation of insulin secretion
GO:0051289  protein homotetramerization
GO:0051259  protein oligomerization
GO:0009749  response to glucose stimulus

Cellular Component

GO:0005945  6-phosphofructokinase complex
GO:0005829  cytosol

Molecular Function

GO:0003872  6-phosphofructokinase activity
GO:0005524  ATP binding
GO:0070061  fructose binding
GO:0004331  fructose-2,6-bisphosphate 2-phosphatase activity
GO:0070095  fructose-6-phosphate binding
GO:0042802  identical protein binding
GO:0019900  kinase binding
GO:0046872  metal ion binding
GO:0048029  monosaccharide binding