RAB5B, member RAS oncogene family

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Synonym

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Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.37 cerebellum:8.32 brain stem:8.02 corpus callosum/glia:- pineal gland:- peripheral nerve:8.47 spine:- retina:- eye:7.83 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:8.20 thymus:8.28 bone marrow:8 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.87 muscle:8.27 esophagus:- stomach:- intestine:7.74 colon:8.31 liver/hepato:- lung:- bladder:- kidney:8.45 pituitary:8.39 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001079936
Gene ID 288779
Unigene ID Rn.33055
Probe set ID rc_AA866364_at  [RG_U34A]
Ensembl ID ENSRNOG00000006130

Orthologous Gene

Human[1]  NM_002868
Mouse[1]  NM_177411

Chromosomal Region

7q11  [1,979,794  -  1,998,540]

Gene Family (Interpro ID)

IPR006688  ADP-ribosylation factor
IPR006689  ARF/SAR superfamily
IPR001019  Guanine nucleotide binding protein (G-protein), alpha subunit
IPR013684  MIRO-like
IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR003577  Ras small GTPase, Ras type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

12477932
18445495

Gene Ontology  (GO ID)

Biological Process

GO:0007032  endosome organization
GO:0015031  protein transport
GO:0030100  regulation of endocytosis
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0030139  endocytic vesicle
GO:0005768  endosome
GO:0005622  intracellular

Molecular Function

GO:0019003  GDP binding
GO:0005525  GTP binding
GO:0030742  GTP-dependent protein binding