protoporphyrinogen oxidase

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:147.50 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:122.90 bone marrow:- adipose:- bone:39 skin:-
GeneChip cerebrum:5.65 cerebellum:5.77 brain stem:5.61 corpus callosum/glia:- pineal gland:- peripheral nerve:5.74 spine:- retina:- eye:5.54 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.46 thymus:6.53 bone marrow:7.53 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:38 ovary:- testis:- heart:116.30 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:53.20        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.92 muscle:5.69 esophagus:- stomach:- intestine:5.82 colon:5.84 liver/hepato:- lung:- bladder:- kidney:6.66 pituitary:6.12 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001105968
Gene ID 289219
Unigene ID Rn.24738
Probe set ID rc_AA859700_g_at  [RG_U34A]
Ensembl ID ENSRNOG00000003567

Orthologous Gene

Human[2]  NM_000309, NM_001122764
Mouse[1]  NM_008911, NM_001122764

Chromosomal Region

13q24  [87,170,602  -  87,174,740]

Gene Family (Interpro ID)

IPR006076  FAD dependent oxidoreductase
IPR013027  FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Link to Pubmed  (Pubmed ID)

3663105
3955059
3996415
6316951
8563760
8852667
9254745
9431441
10486317
11929050
16839620

Gene Ontology  (GO ID)

Biological Process

GO:0006783  heme biosynthetic process
GO:0055114  oxidation reduction
GO:0006779  porphyrin biosynthetic process
GO:0046501  protoporphyrinogen IX metabolic process
GO:0042493  response to drug

Cellular Component

GO:0031305  integral to mitochondrial inner membrane
GO:0031304  intrinsic to mitochondrial inner membrane
GO:0031966  mitochondrial membrane
GO:0005739  mitochondrion

Molecular Function

GO:0004729  oxygen-dependent protoporphyrinogen oxidase activity