CD46 molecule, complement regulatory protein

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_019190
Gene ID 29333
Unigene ID Rn.163242
Probe set ID -
Ensembl ID ENSRNOG00000007917

Orthologous Gene

Human[24]  NM_002389, NM_153826, NM_172350, NM_172351, NM_172352, NM_172353, NM_172359, NM_172361
Mouse[1]  NM_010778, NM_153826, NM_172350, NM_172351, NM_172352, NM_172353, NM_172359, NM_172361

Chromosomal Region

13q27  [110,979,703  -  111,003,407]

Gene Family (Interpro ID)

IPR000436  Sushi/SCR/CCP

Link to Pubmed  (Pubmed ID)

7532466
7690370
9358772
9799332
10469244
10637067
10744069
12055630
12183422
12869763
15215199
15378282
15601919
15726105
16425382
16948860
17214367
17594162
19456309
21177319
21445332
21573156
21852528
22247341

Gene Ontology  (GO ID)

Biological Process

GO:0045916  negative regulation of complement activation
GO:0006508  proteolysis
GO:0007338  single fertilization

Cellular Component

GO:0001669  acrosomal vesicle
GO:0016323  basolateral plasma membrane
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0002079  inner acrosomal membrane
GO:0016021  integral to membrane

Molecular Function

GO:0001848  complement binding
GO:0004175  endopeptidase activity
GO:0004857  enzyme inhibitor activity