NADH dehydrogenase (ubiquinone) Fe-S protein 8

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:107.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:221.20 spine:- retina:- eye:142.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:39 skin:-
GeneChip cerebrum:8.75 cerebellum:9.23 brain stem:9.17 corpus callosum/glia:- pineal gland:- peripheral nerve:9.61 spine:- retina:- eye:7.78 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:9.21 thymus:9.91 bone marrow:8.83 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:114.10 testis:- heart:232.70 muscle:- esophagus:- stomach:- intestine:104.70 colon:289.90     liver/hepato:13.30        lung:-    bladder:- kidney:127.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:170.70 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:10.93 muscle:10.79 esophagus:- stomach:- intestine:9.74 colon:10.33 liver/hepato:- lung:- bladder:- kidney:10.49 pituitary:8.74 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001106322
Gene ID 293652
Unigene ID Rn.3373
Probe set ID rc_AA799479_g_at  [RG_U34A]
Ensembl ID ENSRNOG00000017446

Orthologous Gene

Human[2]  NM_002496
Mouse[5]  NM_144870

Chromosomal Region

1q42  [206,433,597  -  206,437,478]

Gene Family (Interpro ID)

IPR001450  4Fe-4S binding domain
IPR017896  4Fe-4S ferredoxin, iron-sulpur binding domain
IPR009051  Alpha-helical ferredoxin
IPR010226  NADH-quinone oxidoreductase, chain I

Link to Pubmed  (Pubmed ID)

11220739
12477932

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0032981  mitochondrial respiratory chain complex I assembly
GO:0006979  response to oxidative stress

Cellular Component

GO:0005575  cellular_component
GO:0005747  mitochondrial respiratory chain complex I
GO:0005739  mitochondrion

Molecular Function

GO:0051539  4 iron, 4 sulfur cluster binding
GO:0009055  electron carrier activity
GO:0003674  molecular_function
GO:0008137  NADH dehydrogenase (ubiquinone) activity
GO:0003954  NADH dehydrogenase activity