serine (or cysteine) peptidase inhibitor, clade E, member 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:122.90 bone marrow:- adipose:- bone:39 skin:-
GeneChip cerebrum:6.84 cerebellum:6.97 brain stem:6.93 corpus callosum/glia:- pineal gland:- peripheral nerve:7.10 spine:- retina:- eye:5.88 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.93 thymus:5.69 bone marrow:6.70 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:79.60 prostate:- ovary:114.10 testis:329.40 heart:77.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:101.30    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.49 muscle:6.73 esophagus:- stomach:- intestine:5.67 colon:5.73 liver/hepato:- lung:- bladder:- kidney:6.13 pituitary:5.97 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_019197
Gene ID 29366
Unigene ID Rn.22712
Probe set ID A03913cds_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000015461

Orthologous Gene

Human[6]  NM_001136528, NM_001136530, NM_006216
Mouse[1]  NM_009255, NM_001136530, NM_006216

Chromosomal Region

9q34  [79,091,425  -  79,166,330]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1298926
1554734
2337608
2813392
3427015
8261109
8268720
8373421
8889548
8923453
9025067
9102311
9751132
9757068
10473120
11457471
12165407
12524238
12947022
15281096
15354176
16192390
16319172
17379830
18442833
19167525
20819545
20942929
23106098

Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0021683  cerebellar granular layer morphogenesis
GO:0050974  detection of mechanical stimulus involved in sensory perception
GO:0007566  embryo implantation
GO:0060384  innervation
GO:0060291  long-term synaptic potentiation
GO:0042628  mating plug formation
GO:0030195  negative regulation of blood coagulation
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010951  negative regulation of endopeptidase activity
GO:0010466  negative regulation of peptidase activity
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0010757  negative regulation of plasminogen activation
GO:0010544  negative regulation of platelet activation
GO:0042177  negative regulation of protein catabolic process
GO:0045861  negative regulation of proteolysis
GO:0045879  negative regulation of smoothened signaling pathway
GO:0010766  negative regulation of sodium ion transport
GO:0048711  positive regulation of astrocyte differentiation
GO:0010976  positive regulation of neuron projection development
GO:0051966  regulation of synaptic transmission, glutamatergic
GO:0048505  regulation of timing of cell differentiation
GO:0009314  response to radiation
GO:0009611  response to wounding
GO:0032940  secretion by cell
GO:0033363  secretory granule organization

Cellular Component

GO:0043025  cell soma
GO:0005829  cytosol
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0031232  extrinsic to external side of plasma membrane
GO:0016020  membrane
GO:0031594  neuromuscular junction
GO:0031091  platelet alpha granule

Molecular Function

GO:0005539  glycosaminoglycan binding
GO:0008201  heparin binding
GO:0005102  receptor binding
GO:0004867  serine-type endopeptidase inhibitor activity