numb homolog (Drosophila)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:119.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:78.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:318.60 prostate:113.90 ovary:- testis:82.30 heart:38.80 muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:-        lung:152    bladder:- kidney:63.80 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_133287
Gene ID 29419
Unigene ID Rn.102078
Probe set ID -
Ensembl ID ENSRNOG00000009653

Orthologous Gene

Human[8]  NM_001005743, NM_001005744, NM_001005745, NM_003744
Mouse[4]  NM_001136075, NM_010949, NM_001005745, NM_003744

Chromosomal Region

6q31  [107,838,216  -  107,882,303]

Gene Family (Interpro ID)

IPR006020  Phosphotyrosine interaction domain
IPR011993  Pleckstrin homology-type

Link to Pubmed  (Pubmed ID)

8805372
11900468
12477932
12500307
12702648
12876431
12942088
15492044
16105844
16394100
17022975
21150807
21448337
23132739

Gene Ontology  (GO ID)

Biological Process

GO:0034332  adherens junction organization
GO:0007409  axonogenesis
GO:0030154  cell differentiation
GO:0008283  cell proliferation
GO:0030900  forebrain development
GO:0021670  lateral ventricle development
GO:0060487  lung epithelial cell differentiation
GO:0045746  negative regulation of Notch signaling pathway
GO:0007399  nervous system development
GO:0021849  neuroblast division in the subventricular zone
GO:0007405  neuroblast proliferation
GO:0050775  positive regulation of dendrite morphogenesis
GO:0050769  positive regulation of neurogenesis
GO:0030862  positive regulation of polarized epithelial cell differentiation
GO:0045664  regulation of neuron differentiation

Cellular Component

GO:0045177  apical part of cell
GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005737  cytoplasm
GO:0005769  early endosome
GO:0019897  extrinsic to plasma membrane
GO:0016020  membrane
GO:0005634  nucleus

Molecular Function

GO:0045294  alpha-catenin binding
GO:0008013  beta-catenin binding
GO:0045296  cadherin binding
GO:0005515  protein binding