nth (endonuclease III)-like 1 (E.coli)

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Synonym

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Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:78.10 skin:-
GeneChip cerebrum:7.31 cerebellum:7.01 brain stem:7.20 corpus callosum/glia:- pineal gland:- peripheral nerve:7.36 spine:- retina:- eye:7.57 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.51 thymus:7.61 bone marrow:7.56 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:- ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.30 muscle:7.31 esophagus:- stomach:- intestine:7.03 colon:7.42 liver/hepato:- lung:- bladder:- kidney:7.32 pituitary:7.14 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001105728
Gene ID 29541
Unigene ID Rn.14632
Probe set ID rc_H33255_at  [RG_U34A]
Ensembl ID ENSRNOG00000012213

Orthologous Gene

Human[1]  NM_002528
Mouse[1]  NM_008743

Chromosomal Region

10q12  [13,883,284  -  13,889,790]

Gene Family (Interpro ID)

IPR011257  DNA glycosylase
IPR004036  Endonuclease III, conserved site-2
IPR003651  Endonuclease III-like, iron-sulphur cluster loop motif
IPR003583  Helix-hairpin-helix DNA-binding motif, class 1
IPR000445  Helix-hairpin-helix motif
IPR003265  HhH-GPD domain

Link to Pubmed  (Pubmed ID)

16001017
20033472
23352893

Gene Ontology  (GO ID)

Biological Process

GO:0006285  base-excision repair, AP site formation
GO:0006296  nucleotide-excision repair, DNA incision, 5'-to lesion

Cellular Component

GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0051539  4 iron, 4 sulfur cluster binding
GO:0019104  DNA N-glycosylase activity
GO:0003906  DNA-(apurinic or apyrimidinic site) lyase activity
GO:0003690  double-stranded DNA binding
GO:0004519  endonuclease activity