sphingosine-1-phosphate receptor 1

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:107.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:312 thymus:122.90 bone marrow:- adipose:147.20 bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:79.60 prostate:- ovary:114.10 testis:- heart:77.60 muscle:- esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:39.90        lung:253.30    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_017301
Gene ID 29733
Unigene ID Rn.109455
Probe set ID -
Ensembl ID ENSRNOG00000013683

Orthologous Gene

Human[1]  NM_001400
Mouse[1]  NM_007901

Chromosomal Region

2q41  [211,851,304  -  211,855,511]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR002230  Cannabinoid receptor
IPR000987  EDG-1 sphingosine 1-phosphate receptor
IPR004062  EDG-3 sphingosine 1-phosphate receptor
IPR017452  GPCR, rhodopsin-like superfamily
IPR004065  Lysophosphatidic acid receptor
IPR002277  Lysophosphatidic acid receptor EDG-2
IPR001671  Melanocortin/ACTH receptor
IPR000611  Neuropeptide Y receptor
IPR004061  Sphingosine 1-phosphate receptor

Link to Pubmed  (Pubmed ID)

7959012
9765227
10982820
11094076
11214319
11549339
11557736
12477932
14711826
16403835
16990586
17938382
18535287
19493165
20032465
20729401
20844107
21289599
21605625
21613209
21719706
22104144
22445889
22805346
22828274
23969695

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0007420  brain development
GO:0051482  elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0045446  endothelial cell differentiation
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0051497  negative regulation of stress fiber formation
GO:0030182  neuron differentiation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0050927  positive regulation of positive chemotaxis
GO:0032320  positive regulation of Ras GTPase activity
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030155  regulation of cell adhesion
GO:0019226  transmission of nerve impulse

Cellular Component

GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane

Molecular Function

GO:0004930  G-protein coupled receptor activity
GO:0046625  sphingolipid binding