excision repair cross-complementing rodent repair deficiency, complementation group 8

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Synonym

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Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:119.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:110.60 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.54 cerebellum:5.64 brain stem:5.30 corpus callosum/glia:- pineal gland:- peripheral nerve:6.15 spine:- retina:- eye:4.95 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.13 thymus:5.28 bone marrow:4.91 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:82.30 heart:38.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:4.96 muscle:5.16 esophagus:- stomach:- intestine:4.70 colon:4.95 liver/hepato:- lung:- bladder:- kidney:4.67 pituitary:5.96 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001107650
Gene ID 310071
Unigene ID Rn.107979
Probe set ID rc_AA800156_at  [RG_U34A]
Ensembl ID ENSRNOG00000009968

Orthologous Gene

Human[1]  NM_000082
Mouse[3]  NM_028042

Chromosomal Region

2q14  [39,382,976  -  39,420,764]

Gene Family (Interpro ID)

IPR020472  G-protein beta WD-40 repeat, region
IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

12477932
18166977
22824526

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0045739  positive regulation of DNA repair
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0051865  protein autoubiquitination
GO:0000209  protein polyubiquitination
GO:0006979  response to oxidative stress
GO:0009411  response to UV
GO:0010165  response to X-ray
GO:0006283  transcription-coupled nucleotide-excision repair

Cellular Component

GO:0005575  cellular_component
GO:0031464  Cul4A-RING ubiquitin ligase complex
GO:0016363  nuclear matrix
GO:0000109  nucleotide-excision repair complex

Molecular Function

GO:0003674  molecular_function
GO:0032403  protein complex binding
GO:0004842  ubiquitin-protein ligase activity