dual specificity phosphatase 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:491.60 bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:101.30    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001012089
Gene ID 311406
Unigene ID Rn.136933
Probe set ID -
Ensembl ID ENSRNOG00000013862

Orthologous Gene

Human[1]  NM_004418
Mouse[1]  NM_010090

Chromosomal Region

3q36  [114,838,605  -  114,840,779]

Gene Family (Interpro ID)

IPR000340  Dual specificity phosphatase, catalytic domain
IPR020422  Dual specificity phosphatase, subgroup, catalytic domain
IPR014393  Dual specificity protein phosphatase (MAP kinase phosphatase)
IPR008343  MAP kinase phosphatase

Link to Pubmed  (Pubmed ID)

12477932

Gene Ontology  (GO ID)

Biological Process

GO:0001706  endoderm formation
GO:0000188  inactivation of MAPK activity
GO:0006470  protein amino acid dephosphorylation
GO:0042981  regulation of apoptosis

Cellular Component

GO:0005654  nucleoplasm

Molecular Function

GO:0017017  MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0051019  mitogen-activated protein kinase binding
GO:0004721  phosphoprotein phosphatase activity
GO:0004725  protein tyrosine phosphatase activity