Rac GTPase-activating protein 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.92 cerebellum:6.41 brain stem:6.19 corpus callosum/glia:- pineal gland:- peripheral nerve:6.81 spine:- retina:- eye:6.95 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.60 thymus:8.55 bone marrow:8.37 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.79 muscle:5.64 esophagus:- stomach:- intestine:6.73 colon:7.49 liver/hepato:- lung:- bladder:- kidney:5.82 pituitary:6 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108112
Gene ID 315298
Unigene ID -
Probe set ID rc_AA893717_at  [RG_U34A]
Ensembl ID ENSRNOG00000018187

Orthologous Gene

Human[3]  NM_001126103, NM_001126104, NM_013277
Mouse[2]  NM_012025, NM_001126104, NM_013277

Chromosomal Region

7q36  [138,366,356  -  138,395,716]

Gene Family (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

12477932

Gene Ontology  (GO ID)

Biological Process

GO:0000910  cytokinesis
GO:0000915  cytokinesis, actomyosin contractile ring formation
GO:0007108  cytokinesis, initiation of separation
GO:0009790  embryonic development
GO:0032467  positive regulation of cytokinesis
GO:0043547  positive regulation of GTPase activity
GO:0051988  regulation of attachment of spindle microtubules to kinetochore
GO:0007283  spermatogenesis
GO:0051256  spindle midzone assembly involved in mitosis
GO:0008272  sulfate transport

Cellular Component

GO:0032154  cleavage furrow
GO:0005622  intracellular
GO:0030496  midbody
GO:0005634  nucleus
GO:0051233  spindle midzone

Molecular Function

GO:0043014  alpha-tubulin binding
GO:0048487  beta-tubulin binding
GO:0043015  gamma-tubulin binding
GO:0005096  GTPase activator activity
GO:0046872  metal ion binding
GO:0008017  microtubule binding
GO:0019901  protein kinase binding