toll-like receptor 7

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:4.43 cerebellum:4.10 brain stem:4.36 corpus callosum/glia:- pineal gland:- peripheral nerve:4.57 spine:- retina:- eye:4.39 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.41 thymus:4.53 bone marrow:4.80 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:4.40 muscle:4.20 esophagus:- stomach:- intestine:4.36 colon:4.34 liver/hepato:- lung:- bladder:- kidney:4.37 pituitary:4.49 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001097582
Gene ID 317468
Unigene ID -
Probe set ID rc_AA893666_at  [RG_U34A]
Ensembl ID ENSRNOG00000004249

Orthologous Gene

Human[1]  NM_016562
Mouse[1]  NM_133211

Chromosomal Region

Xq21  [47,330,737  -  47,356,841]

Gene Family (Interpro ID)

IPR004075  Interleukin-1 receptor, type I/Toll precursor
IPR000157  Toll-Interleukin receptor

Link to Pubmed  (Pubmed ID)

12781911
16973131
18256364
19386802
19944565
21235323
21364926
21753151
22765640
23157229

Gene Ontology  (GO ID)

Biological Process

GO:0071260  cellular response to mechanical stimulus
GO:0051607  defense response to virus
GO:0007252  I-kappaB phosphorylation
GO:0002282  microglial cell activation during immune response
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0052033  pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0032722  positive regulation of chemokine production
GO:0045356  positive regulation of interferon-alpha biosynthetic process
GO:0045359  positive regulation of interferon-beta biosynthetic process
GO:0045078  positive regulation of interferon-gamma biosynthetic process
GO:0032755  positive regulation of interleukin-6 production
GO:0045416  positive regulation of interleukin-8 biosynthetic process
GO:0032757  positive regulation of interleukin-8 production
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0042221  response to chemical stimulus
GO:0034154  toll-like receptor 7 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0032009  early phagosome
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005764  lysosome
GO:0005886  plasma membrane

Molecular Function

GO:0003725  double-stranded RNA binding
GO:0008144  drug binding
GO:0003727  single-stranded RNA binding
GO:0035197  siRNA binding
GO:0004888  transmembrane receptor activity