pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.63 cerebellum:8.24 brain stem:7.92 corpus callosum/glia:- pineal gland:- peripheral nerve:7.79 spine:- retina:- eye:6.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.69 thymus:6.94 bone marrow:6.24 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:38 ovary:228.20 testis:- heart:77.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:152    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.75 muscle:6.37 esophagus:- stomach:- intestine:7.92 colon:8.40 liver/hepato:- lung:- bladder:- kidney:7.69 pituitary:9.11 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001079894
Gene ID 361659
Unigene ID Rn.17662
Probe set ID AF034237_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000020497

Orthologous Gene

Human[2]  NM_001001974, NM_001195608, NM_021622
Mouse[1]  NM_133942, NM_001195608, NM_021622

Chromosomal Region

1q37  [190,187,202  -  190,238,308]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology
IPR001605  Spectrin/pleckstrin-like

Link to Pubmed  (Pubmed ID)

12477932

Gene Ontology  (GO ID)

Biological Process

GO:0008209  androgen metabolic process
GO:0050853  B cell receptor signaling pathway
GO:0008150  biological_process
GO:0070301  cellular response to hydrogen peroxide
GO:0045184  establishment of protein localization
GO:0008210  estrogen metabolic process
GO:0060325  face morphogenesis
GO:0008585  female gonad development
GO:0033327  Leydig cell differentiation
GO:0001553  luteinization
GO:0035264  multicellular organism growth
GO:0051898  negative regulation of protein kinase B signaling cascade
GO:0060021  palate development
GO:0014065  phosphoinositide 3-kinase cascade
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0009791  post-embryonic development
GO:0031529  ruffle organization
GO:0048705  skeletal system morphogenesis
GO:0007283  spermatogenesis

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0032587  ruffle membrane

Molecular Function

GO:0003674  molecular_function
GO:0030165  PDZ domain binding
GO:0043325  phosphatidylinositol-3,4-bisphosphate binding