SIN3 homolog A, transcription regulator (yeast)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:357.10 vein:- lymphnode:- peripheral blood:- spleen:234 thymus:245.80 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:151.80 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:118.40 thyroid/parathyroid:- adrenal gland:- pancreas:170.70 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108761
Gene ID 363067
Unigene ID Rn.63749
Probe set ID -
Ensembl ID ENSRNOG00000032254

Orthologous Gene

Human[3]  NM_001145357, NM_001145358, NM_015477
Mouse[9]  NM_001110350, NM_001110351, NM_011378

Chromosomal Region

8q24  [60,843,640  -  60,884,764]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10491605
15322089
16776654
18945670
19289167

Gene Ontology  (GO ID)

Biological Process

GO:0002218  activation of innate immune response
GO:0007568  aging
GO:0034613  cellular protein localization
GO:0071333  cellular response to glucose stimulus
GO:0006260  DNA replication
GO:0001701  in utero embryonic development
GO:0043066  negative regulation of apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0031937  positive regulation of chromatin silencing
GO:0002230  positive regulation of defense response to virus by host
GO:0010971  positive regulation of G2/M transition of mitotic cell cycle
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006476  protein amino acid deacetylation
GO:0043619  regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0006355  regulation of transcription, DNA-dependent
GO:0051595  response to methylglyoxal
GO:0010243  response to organic nitrogen

Cellular Component

GO:0000785  chromatin
GO:0000776  kinetochore
GO:0005634  nucleus
GO:0043234  protein complex
GO:0016580  Sin3 complex
GO:0005667  transcription factor complex
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0033558  protein deacetylase activity
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding