endothelin 3

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.90 cerebellum:7.06 brain stem:7 corpus callosum/glia:- pineal gland:- peripheral nerve:6.41 spine:- retina:- eye:7.06 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.03 thymus:6.89 bone marrow:7.23 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.07 muscle:7.36 esophagus:- stomach:- intestine:6.97 colon:6.72 liver/hepato:- lung:- bladder:- kidney:6.85 pituitary:7.23 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001077650
Gene ID 366270
Unigene ID Rn.201692
Probe set ID E02223cds_f_at  [RG_U34A]
Ensembl ID ENSRNOG00000007477

Orthologous Gene

Human[8]  NM_000114, NM_207032, NM_207033, NM_207034
Mouse[2]  NM_007903, NM_207032, NM_207033, NM_207034

Chromosomal Region

3q43  [166,491,368  -  166,514,051]

Gene Family (Interpro ID)

IPR020475  Bibrotoxin/Sarafotoxin-D
IPR001928  Endothelin-like toxin

Link to Pubmed  (Pubmed ID)

1299957
1378731
1422599
1533364
1735599
1860178
2054939
3045827
8106108
8630502
8696331
8858922
9165019
9359047
9716657
11414314
12184995
12234805
15093706
15344879
15629454
15949640
16023617
16287488
18682267
18771698
18850267
23370722
24040226

Gene Ontology  (GO ID)

Biological Process

GO:0014824  artery smooth muscle contraction
GO:0007166  cell surface receptor linked signal transduction
GO:0048016  inositol phosphate-mediated signaling
GO:0030318  melanocyte differentiation
GO:0046888  negative regulation of hormone secretion
GO:0001755  neural crest cell migration
GO:0030182  neuron differentiation
GO:0030593  neutrophil chemotaxis
GO:0030072  peptide hormone secretion
GO:0008284  positive regulation of cell proliferation
GO:0010460  positive regulation of heart rate
GO:0046887  positive regulation of hormone secretion
GO:0002690  positive regulation of leukocyte chemotaxis
GO:0043406  positive regulation of MAP kinase activity
GO:0045840  positive regulation of mitosis
GO:0030334  regulation of cell migration
GO:0046928  regulation of neurotransmitter secretion
GO:0048070  regulation of pigmentation during development
GO:0003100  regulation of systemic arterial blood pressure by endothelin
GO:0019229  regulation of vasoconstriction
GO:0042310  vasoconstriction
GO:0014826  vein smooth muscle contraction

Cellular Component

GO:0005575  cellular_component
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0031705  bombesin receptor binding
GO:0005179  hormone activity