mediator complex subunit 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:71.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:75.90 ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:314 colon:-     liver/hepato:26.60        lung:101.30    bladder:- kidney:63.80 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001081351
Gene ID 497991
Unigene ID Rn.4262
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

10q31  [86,915,421  -  86,959,422]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10037764
11306337
12034878
12189208
12270043
15632090
16394250
17786964
20702579

Gene Ontology  (GO ID)

Biological Process

GO:0006702  androgen biosynthetic process
GO:0030521  androgen receptor signaling pathway
GO:0001525  angiogenesis
GO:0007420  brain development
GO:0043010  camera-type eye development
GO:0000902  cell morphogenesis
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0071383  cellular response to steroid hormone stimulus
GO:0006260  DNA replication
GO:0035050  embryonic heart tube development
GO:0035162  embryonic hemopoiesis
GO:0035116  embryonic hindlimb morphogenesis
GO:0001892  embryonic placenta development
GO:0048822  enucleate erythrocyte development
GO:0060750  epithelial cell proliferation involved in mammary gland duct elongation
GO:0070371  ERK1 and ERK2 cascade
GO:0048821  erythrocyte development
GO:0045444  fat cell differentiation
GO:0007507  heart development
GO:0001701  in utero embryonic development
GO:0030216  keratinocyte differentiation
GO:0007595  lactation
GO:0002088  lens development in camera-type eye
GO:0001889  liver development
GO:0060745  mammary gland branching involved in pregnancy
GO:0060744  mammary gland branching involved in thelarche
GO:0033598  mammary gland epithelial cell proliferation
GO:0030224  monocyte differentiation
GO:0042789  mRNA transcription from RNA polymerase II promoter
GO:0007275  multicellular organismal development
GO:0043066  negative regulation of apoptosis
GO:0010839  negative regulation of keratinocyte proliferation
GO:0045665  negative regulation of neuron differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0009887  organ morphogenesis
GO:0031100  organ regeneration
GO:0033148  positive regulation of estrogen receptor signaling pathway
GO:0070318  positive regulation of G0 to G1 transition
GO:0010628  positive regulation of gene expression
GO:0060335  positive regulation of interferon-gamma-mediated signaling pathway
GO:0045618  positive regulation of keratinocyte differentiation
GO:0033601  positive regulation of mammary gland epithelial cell proliferation
GO:0033160  positive regulation of protein import into nucleus, translocation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006356  regulation of transcription from RNA polymerase I promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0070562  regulation of vitamin D receptor signaling pathway
GO:0003406  retinal pigment epithelium development
GO:0030518  steroid hormone receptor signaling pathway
GO:0006590  thyroid hormone generation
GO:0002154  thyroid hormone mediated signaling pathway
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0003222  ventricular trabecular myocardium morphogenesis

Cellular Component

GO:0000785  chromatin
GO:0016592  mediator complex
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0032993  protein-DNA complex

Molecular Function

GO:0003682  chromatin binding
GO:0031490  chromatin DNA binding
GO:0003677  DNA binding
GO:0030331  estrogen receptor binding
GO:0050693  LBD domain binding
GO:0016922  ligand-dependent nuclear receptor binding
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257  nuclear hormone receptor binding
GO:0042975  peroxisome proliferator activated receptor binding
GO:0032403  protein complex binding
GO:0004872  receptor activity
GO:0042974  retinoic acid receptor binding
GO:0046966  thyroid hormone receptor binding
GO:0030375  thyroid hormone receptor coactivator activity
GO:0003713  transcription coactivator activity
GO:0003712  transcription cofactor activity
GO:0008134  transcription factor binding
GO:0042809  vitamin D receptor binding