L1 cell adhesion molecule

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.90 cerebellum:9.34 brain stem:9.25 corpus callosum/glia:- pineal gland:- peripheral nerve:8.46 spine:- retina:- eye:8.63 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:8.12 thymus:8.25 bone marrow:8.14 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:8.38 muscle:8.25 esophagus:- stomach:- intestine:8.24 colon:8.14 liver/hepato:- lung:- bladder:- kidney:8.46 pituitary:8.17 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_017345
Gene ID 50687
Unigene ID Rn.10378
Probe set ID X59149_at  [RG_U34A]
Ensembl ID ENSRNOG00000037274

Orthologous Gene

Human[6]  NM_000425, NM_001143963, NM_024003
Mouse[2]  NM_008478, NM_001143963, NM_024003

Chromosomal Region

Xq37  [159,784,796  -  159,991,345]

Gene Family (Interpro ID)

IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR013106  Immunoglobulin V-set
IPR003596  Immunoglobulin V-set, subgroup
IPR009134  Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal

Link to Pubmed  (Pubmed ID)

1894011
2466966
2723751
7920659
7920660
11152476
11948808
12070130
12453492
12900915
13678974
14608600
14705138
15803510
15880726
15905095
15911348
16022864
16298234
16424028
16554297
16686695
17093074
17151951
17234591
17640175
17873897
18430502
18464795
18478542
18519736
19185025
19565280
19746433
19995872
20018220
20124415
20162456
20419098
20463227
20964729
21376041
21395909
21671795
21884525
22186713
22349829
23050935

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0007155  cell adhesion
GO:0030154  cell differentiation
GO:0007166  cell surface receptor linked signal transduction
GO:0033631  cell-cell adhesion mediated by integrin
GO:0071361  cellular response to ethanol
GO:0007157  heterophilic cell adhesion
GO:0007156  homophilic cell adhesion
GO:0034109  homotypic cell-cell adhesion
GO:0007159  leukocyte adhesion
GO:0007399  nervous system development
GO:0031175  neuron projection development
GO:0050850  positive regulation of calcium-mediated signaling
GO:0022409  positive regulation of cell-cell adhesion

Cellular Component

GO:0009986  cell surface
GO:0005768  endosome
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane
GO:0042734  presynaptic membrane
GO:0043195  terminal button

Molecular Function

GO:0042802  identical protein binding
GO:0005178  integrin binding
GO:0030165  PDZ domain binding
GO:0043621  protein self-association
GO:0033691  sialic acid binding