lethal giant larvae homolog 1 (Drosophila)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.80 cerebellum:- brain stem:- corpus callosum/glia:20408.20 pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:147.20 bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:75.90 ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:101.30    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_152844
Gene ID 54265
Unigene ID Rn.122316
Probe set ID -
Ensembl ID ENSRNOG00000003948

Orthologous Gene

Human[2]  NM_004140
Mouse[3]  NM_001159404, NM_001159405, NM_008502

Chromosomal Region

10q22  [46,845,810  -  46,859,100]

Gene Family (Interpro ID)

IPR020472  G-protein beta WD-40 repeat, region
IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

8889548
12012002
12792798
15632090
23032931

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0030866  cortical actin cytoskeleton organization
GO:0006887  exocytosis
GO:0006893  Golgi to plasma membrane transport
GO:0035090  maintenance of apical/basal cell polarity
GO:0032851  positive regulation of Rab GTPase activity
GO:0006461  protein complex assembly

Cellular Component

GO:0030424  axon
GO:0030864  cortical actin cytoskeleton
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0031901  early endosome membrane
GO:0000137  Golgi cis cisterna
GO:0000139  Golgi membrane
GO:0032588  trans-Golgi network membrane

Molecular Function

GO:0019901  protein kinase binding
GO:0005097  Rab GTPase activator activity
GO:0017137  Rab GTPase binding