SMAD family member 5

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:78.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:38 ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_021692
Gene ID 59328
Unigene ID Rn.146857
Probe set ID -
Ensembl ID ENSRNOG00000022870

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

17p14  [13,813,734  -  13,832,742]

Gene Family (Interpro ID)

IPR003619  MAD homology 1, Dwarfin-type
IPR013019  MAD homology, MH1
IPR003070  Orphan nuclear receptor
IPR003072  Orphan nuclear receptor, NOR1 type
IPR001132  SMAD domain, Dwarfin-type
IPR017855  SMAD domain-like
IPR008984  SMAD/FHA domain
IPR001723  Steroid hormone receptor

Link to Pubmed  (Pubmed ID)

9264367
11920662
12477932
16361357
16687449
17347486
17967875
20079400
20522807
21515935
22500633

Gene Ontology  (GO ID)

Biological Process

GO:0030509  BMP signaling pathway
GO:0060348  bone development
GO:0060048  cardiac muscle contraction
GO:0051216  cartilage development
GO:0071407  cellular response to organic cyclic substance
GO:0009880  embryonic pattern specification
GO:0030218  erythrocyte differentiation
GO:0007281  germ cell development
GO:0001880  Mullerian duct regression
GO:0001503  ossification
GO:0002051  osteoblast fate commitment
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0030278  regulation of ossification
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001657  ureteric bud development

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0046872  metal ion binding
GO:0003700  transcription factor activity
GO:0031625  ubiquitin protein ligase binding