chromodomain helicase DNA binding protein 8

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:95.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:4444.40 eye:106.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:147.20 bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:75.90 ovary:- testis:82.30 heart:96.90 muscle:- esophagus:- stomach:- intestine:209.30 colon:289.90     liver/hepato:53.20        lung:-    bladder:- kidney:- pituitary:236.90 thyroid/parathyroid:- adrenal gland:- pancreas:227.60 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_022933
Gene ID 65027
Unigene ID Rn.98337
Probe set ID -
Ensembl ID ENSRNOG00000025011

Orthologous Gene

Human[1]  NM_001170629, NM_020920
Mouse[1]  NM_201637, NM_020920

Chromosomal Region

15p14  [27,642,767  -  27,704,443]

Gene Family (Interpro ID)

IPR000953  Chromo domain
IPR016197  Chromo domain-like
IPR013041  Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain
IPR014001  DEAD-like helicase, N-terminal
IPR014021  Helicase, superfamily 1/2, ATP-binding domain

Link to Pubmed  (Pubmed ID)

10921920
11744694
23071553

Gene Ontology  (GO ID)

Biological Process

GO:0043044  ATP-dependent chromatin remodeling
GO:0032508  DNA duplex unwinding
GO:0001701  in utero embryonic development
GO:0043066  negative regulation of apoptosis
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045945  positive regulation of transcription from RNA polymerase III promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0071339  MLL1 complex
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0070016  armadillo repeat domain binding
GO:0005524  ATP binding
GO:0008013  beta-catenin binding
GO:0003677  DNA binding
GO:0003678  DNA helicase activity
GO:0008094  DNA-dependent ATPase activity
GO:0042393  histone binding
GO:0035064  methylated histone residue binding
GO:0002039  p53 binding
GO:0005515  protein binding